. . . "Metiamide binds to an H2-receptor located on the basolateral membrane of the gastric parietal cell, blocking histamine effects. This competitive inhibition results in reduced gastric acid secretion and a reduction in gastric volume and acidity."@en . . . . "Metiamidum"@en . . . . . . . . . . . "Potential in the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion."@en . . . . . . . . . . "Methiamide"@en . "Metiamide is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide. It was an intermediate compound in the development of the successful anti-ulcer drug cimetidine."@en . . . . . " "@en . "Metiamide"@en . . . . . . "34839-70-8"@en . . . "experimental"@en . . . . "Metiamida"@en .