. "1,2-Dimercapto-3-propanol"@en . "2,3-Mercaptopropanol"@en . . . "British antilewisite"@en . "59-52-9"@en . "Dithioglycerine"@en . . "# Walshe JM: The conquest of Wilson's disease. Brain. 2009 Aug;132(Pt 8):2289-95. Epub 2009 Jul 13. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/19596747 # Boscolo M, Antonucci S, Volpe AR, Carmignani M, Di Gioacchino M: Acute mercury intoxication and use of chelating agents. J Biol Regul Homeost Agents. 2009 Oct-Dec;23(4):217-23. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/20003760 # Flora SJ, Pachauri V: Chelation in metal intoxication. Int J Environ Res Public Health. 2010 Jul;7(7):2745-88. Epub 2010 Jun 28. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/20717537 # Andersen O: Chemical and biological considerations in the treatment of metal intoxications by chelating agents. Mini Rev Med Chem. 2004 Jan;4(1):11-21. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/14754439"@en . . . . "1,2-Dithioglycerol"@en . "Urine."@en . . "Dimercaprol"@en . . "Dithioglycerol"@en . "The intramuscular LD50 in rats is approximately 105 mg/kg; intraperitoneally 140 mg/kg. The intraperitoneal LD80 in mice is approximately 125 mg/kg. Dimercaprol has been shown in animal experiments to increase brain deposition of arsenite, organic mercury compounds and increase the toxicity of cadmium and lead. Dimercaprol has been shown to induce seizure in animal studies and also is nephrotoxic. "@en . "2,3-Dimercapto-1-propanol"@en . . . . . . "British Anti-Lewisite"@en . . . . . . . "2,3-Dimercaptol-1-propanol"@en . "Sulfactin"@en . . "After intra-muscular injection."@en . . . " "@en . . . . . . . . . . "For the treatment of arsenic, gold and mercury poisoning. Indicated in acute lead poisoning when used concomitantly with edetate calcium disodium (DB00974)."@en . . . . . . . "The drug has a short half life."@en . . . "2,3-Dithiopropanol"@en . "Dimercaprolum"@en . "2,3-Dimercapro"@en . . . . "The sulfhydryl groups of dimercaprol form complexes with certain heavy metals thus preventing or reversing the metallic binding of sulfhydryl-containing enzymes. The complex is excreted in the urine."@en . "3-Hydroxy-1,2-propanedithiol"@en . . "approved"@en . "alpha,beta-Dithioglycerol"@en . . "Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. Dimercaprol is a potentially toxic drug, and its use may be accompanied by multiple side effects."@en . . "2,3-Mercaptopropan-1-ol"@en . . "Dimercaptopropanol"@en . "2,3-Dimercaptopropanol"@en . . "Peppel, W.J. and Signaigo, F.K.; U.S. Patent 2,402,665; June 25,1946; assigned to E.I. du Pont de Nemwrs & Company."@en . "BAL"@en . .