. . "Norelgestromin inhibits estrone sulfatase, which converts sulfated steroid precursors to estrogen during pregnancy. Norgelgestromin/ethinylestradiol suppresses follicular development, induces changes to the endometrium, which decreases chances of implantation and thickens the cervical mucus, impeding sperm swimming into the uterus. It also has similar agonisting binding affinities as its parent compound, Norgestimate, for progesterone and estrogen receptors. "@en . . . . "Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch."@en . . . . . . "Norelgestromin"@en . . "approved"@en . . . . . " "@en . . . . . "17-Deacylnorgestimate"@en . . . "# Goa KL, Warner GT, Easthope SE: Transdermal ethinylestradiol/norelgestromin: a review of its use in hormonal contraception. Treat Endocrinol. 2003;2(3):191-206. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/15966567 # Henzl MR: Norgestimate. From the laboratory to three clinical indications. J Reprod Med. 2001 Jul;46(7):647-61. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/11499185 # Abrams LS, Skee DM, Wong FA, Anderson NJ, Leese PT: Pharmacokinetics of norelgestromin and ethinyl estradiol from two consecutive contraceptive patches. J Clin Pharmacol. 2001 Nov;41(11):1232-7. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/11697756"@en . "53016-31-2"@en . . "Norelgestromin is used for contraception and menopausal hormonal therapy. Norelgestromin may potentially be used in breast cancer treatment due to its inhibitory effect on estrone sulfatase . They convert sulfated steroid precursors to estrogen during pregnancy. "@en . . . . . . . . . . "Zoltan Tuba, Sandor Maho, Gyorgy Keseru, Jozsef Kozma, Janos Horvath, Gabor Balogh, \"Process of making isomers of norelgestromin and methods using the same.\" U.S. Patent US20050032764, issued February 10, 2005."@en . . . . .