. . . . "Bezitramide is a narcotic analgesic which was discovered in 1961, clinically tested around the 1970's [1], and marketed under the name Burgodin(R). After cases of fatal overdose in the Netherlands in 2004 the drug was withdrawn from the market. In the United States Bezitramide was never been approved for clinical use. It is presently an illegal substance classified under Schedule II of the Controlled Substances Act. [wiki]"@en . . "A narcotic analgesic once used for the treatment of severe chronic pain. [1] "@en . "Bezitramide"@en . . . . . . . . . . "15301-48-1"@en . . . . "Less than 0.3% of the dose was excreted unchanged in the urine. High concentrations in feces suggested incomplete absorption of biliary excretion. Experiments in rats demonstrated extensive (up to 70%) biliary excretion, and less than 3% urinary excretion. [1] "@en . " "@en . . . . "Bezitramide has poor water solubility, thus administration is restricted to the oral route. [1]"@en . "1-[1-(3-Cyano-3,3-diphenylpropyl)-4-piperidinyl]-1,3-dihydro-3-(1-oxopropyl)-2H-benzimidazol-2-one"@en . . "11-24h. [1] "@en . . . . . . "1. Meijer, D. K. F., et al. \"Pharmacokinetics of the oral narcotic analgesic bezitramide and preliminary observations on its effect on experimentally induced pain.\" European journal of clinical pharmacology 27.5 (1984): 615-618."@en . . "illicit"@en . . . . . . "withdrawn"@en . "experimental"@en . . . . .