"Paromomycin i"@en . "Paromomycine"@en . "Hydroxymycin"@en . . " "@en . "R 400"@en . . "For the treatment of acute and chronic intestinal amebiasis (it is not effective in extraintestinal amebiasis). Also for the management of hepatic coma as adjunctive therapy."@en . . . . "Aminosidin"@en . . . "Take with food."@en . . . . "Enteric bacteria and other eubacteria"@en . . . . . . . "approved"@en . "Paucimycinum"@en . . . . . . . . "Aminosidine"@en . . "7542-37-2"@en . . . . . " "@en . . . "Paromomycin"@en . . "Paromomicina"@en . . . . . . . "investigational"@en . . "Paromomycinum"@en . "Catenulin"@en . . "PAROMOMYCIN"@en . "An oligosaccharide antibiotic produced by various streptomyces. [PubChem]"@en . "(1R,2R,3S,4R,6S)-4,6-Diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside"@en . "R-400"@en . "Federico Arcamone, Giuseppe Cassinelli, \"Paromomycin derivatives and process for the preparation thereof.\" U.S. Patent US4021601, issued October, 1967."@en . "Crestomycin"@en . . . "# Vicens Q, Westhof E: Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site. Structure. 2001 Aug;9(8):647-58. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/11587639"@en . "Monomycin a"@en . "Paucimycin"@en . . . . . . . "Estomycin"@en . "Poorly absorbed after oral administration, with almost 100% of the drug recoverable in the stool."@en . "Neomycin e"@en . "Paromomycin inhibits protein synthesis by binding to 16S ribosomal RNA. Bacterial proteins are synthesized by ribosomal RNA complexes which are composed of 2 subunits, a large subunit (50s) and small (30s) subunit, which forms a 70s ribosomal subunit. tRNA binds to the top of this ribosomal structure. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced. Continuous production of defective proteins eventually leads to bacterial death."@en . "Zygomycin a1"@en .