. "Overdosage of cephalosporins can cause cerebral irritation leading to convulsions. "@en . . . . . . . . . . . . . . "Ceftibuten is a third-generation cephalosporin antibiotic. It is an orally-administered agent. Cefalexin is used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis."@en . . . . . . . . . . . . . . . . "97519-39-6"@en . . . . . . "Ceftibuteno"@en . "Ceftibutenum"@en . "Ceftibuten"@en . "approved"@en . . "(+)-(6R,7R)-7-((Z)-2-(2-amino-4-Thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid"@en . "Ceftibuten is excreted in the urine; 95% of the administered radioactivity was recovered either in urine or feces."@en . . . "Rapidly absorbed following oral administration."@en . . . . "cis-Ceftibuten"@en . . . . . . . . . "Enteric bacteria and other eubacteria"@en . " "@en . . . . . . "Ceftibutene"@en . "Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis."@en . "Used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis."@en . "* 0.21 L/kg [adult subjects] * 0.5 L/kg [fasting pediatric patients]"@en . "Ceftibuten is 65% bound to plasma proteins. The protein binding is independent of plasma ceftibuten concentration."@en . .