. "Pipecuronium"@en . "Pipecuronium"@en . . . "Humans and other mammals"@en . . . . . "Distribution Normal renal function: 6.22 (range, 1.34 to 10.66) minutes. Renal function impairment: 4.33 (range, 1.69 to 6.17) minutes. Elimination Normal renal function: 1.7 (range, 0.9 to 2.7) hours. The elimination half-life is not altered by hypothermia and bypass. Renal function impairment: 4 (range, 2 to 8.2) hours. [PharmGKB]"@en . . " "@en . . "68399-58-6"@en . . . . . "Pipecurium"@en . . "approved"@en . . . . " "@en . . . . "Nondepolarizing neuromuscular blocking agents inhibit neuromuscular transmission by competing with acetylcholine for the cholinergic receptors of the motor end plate, thereby reducing the response of the end plate to acetylcholine. This type of neuromuscular block is usually antagonized by anticholinesterase agents."@en . . . . . . . . . . . "Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent."@en . . . . . . "Used as a muscle relaxant during anesthesia and surgical procedures."@en . .