"Thiamylal binds at a distinct binding site associated with a Cl^- ionopore at the GABA_A receptor, increasing the duration of time for which the Cl^- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged."@en . "5-Allyl-5-(1-methylbutyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione"@en . "Thiamylal"@en . "Intravenous LD50 in rat is 51 mg/kg."@en . "Although no studies have been performed on humans, the half-life in cats is 14.3 hours."@en . . "Humans and other mammals"@en . "approved"@en . . . "Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state."@en . . . . "5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid"@en . . . . . "Rapidly absorbed (high lipid solubility)."@en . . . . . . "77-27-0"@en . . . . . . . "dihydro-5-(1-Methylbutyl)-5-(2-propenyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione"@en . . . "5-Allyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione"@en . . . . . . . . . . "A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. (From Martindale, The Extra Pharmacopoeia, 30th ed, p919)"@en . . "Thioseconal"@en . . . . . . . . "Thiamylal"@en . . . .