. "Sertaconazole nitrate is an antifungal medication of the imidazole class. It is available as a cream to treat skin infections such as athlete's foot. [Wikipedia]"@en . . "For the topical treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum."@en . . . . "Sertaconazolum"@en . . "Sertaconazole"@en . "Sertaconazole"@en . . "Yeast and other fungi"@en . . . . . . . . . "Bioavailability is negligible."@en . "Demofix"@en . . . . . . . . . . . . . . . . . . . . "approved"@en . . . . . . . . ">99% to plasma"@en . . "Sertaconazol"@en . . " "@en . . . "Ertaczo"@en . "Sertaconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Sertaconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis."@en . "99592-32-2"@en . . .