. . . . . "Phenurone"@en . "May be taken with food if stomach upset occurs."@en . "Phenacemide is used to control certain seizures in the treatment of epilepsy. This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures."@en . "Phenacemide"@en . . . . . "63-98-9"@en . . . "Almost completely absorbed."@en . "Phenacemide binds to and blocks neuronal sodium channels or voltage sensitive calcium channels. This blocks or suppresses neuronal depolarization and hypersynchronization. Hypersynchronization is what often causes seizures."@en . "approved"@en . . "# Coker SB: The use of phenacemide for intractable partial complex epilepsy in children. Pediatr Neurol. 1986 Jul-Aug;2(4):230-2. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/3508693 # Coker SB, Holmes EW, Egel RT: Phenacemide therapy of complex partial epilepsy in children: determination of plasma drug concentrations. Neurology. 1987 Dec;37(12):1861-6. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/3683877"@en . . . "Oral, mouse: LD₅₀ = 987 mg/kg; Oral, rabbit: LD₅₀ = 2500 mg/kg; Oral, rat: LD₅₀ = 1600 mg/kg"@en . . . . . . . "Humans and other mammals"@en . . . . . . . . . . . . . . . "Used to control certain seizures in the treatment of epilepsy."@en . . . . . . . . . "22-25 hours."@en .