. . . . . . . . . . . . . . . . . . . . . . "# Ramirez Chanona N, del Rio Navarro BE, Perez Martin J: [Efficacy of mequitazine (Primalan) on the relief of symptoms of allergic rhinoconjunctivitis in children. Documented clinical experience] Rev Alerg Mex. 2005 Nov-Dec;52(6):221-5. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/16568706 # Theunissen EL, Vermeeren A, van Oers AC, van Maris I, Ramaekers JG: A dose-ranging study of the effects of mequitazine on actual driving, memory and psychomotor performance as compared to dexchlorpheniramine, cetirizine and placebo. Clin Exp Allergy. 2004 Feb;34(2):250-8. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/14987305 # Nakamura K, Yokoi T, Kodama T, Inoue K, Nagashima K, Shimada N, Shimizu T, Kamataki T: Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes. J Pharmacol Exp Ther. 1998 Feb;284(2):437-42. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/9454781 # Persi L, Dupin O, Arnaud B, Trinquand C, Michel FB, Bousquet J: Efficacy of mequitazine in comparison with placebo assessed by ocular challenge with allergen in allergic conjunctivitis. Allergy. 1997 Apr;52(4):451-4. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/9188930"@en . . . "Mequitazinum"@en . . "Kitazemin"@en . "approved"@en . "Mequitazine binds to the histamine H1 receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine."@en . . "Mequitazine"@en . . . . . . "29216-28-2"@en . . "For the treatment of Hay fever, urticaria (hives) and allergic rhinitis"@en . "Charles Mioskowski, Vanessa Gonnot, Rachid Baati, Marc Nicolas, \"NOVEL QUINUCLIDINE DERIVATIVE USEFUL IN THE PREPARATION OF MEQUITAZINE.\" U.S. Patent US20100105897, issued April 29, 2010."@en . " "@en . . . "Mequitazina"@en . . . "Mequitazine is a histamine H1 antagonist (antihistamine). It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies."@en . . "Humans and other mammals"@en . . . .