"Spectinomycine"@en . . "Espectinomicina"@en . . . "Spectinomycin"@en . "David R. White, \"Intermediate compounds in the preparation of spectinomycin.\" U.S. Patent US4344882, issued August, 1966."@en . "SCM"@en . . . . "Spectinomicina"@en . . . . . . . . . . . . . "Actinospectacina"@en . . . . . . "Spectinomycinum"@en . . . "Not significant"@en . " "@en . "Spectinomycin is an inhibitor of protein synthesis in the bacterial cell; the site of action is the 30S ribosomal subunit. It is bactericidal in its action."@en . . . "1695-77-8"@en . . . "An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea."@en . . . . . . "approved"@en . . "Acute oral toxicity (LD₅₀): >5000 mg/kg [Rat]. Information on overdosage in humans is not available."@en . . "Enteric bacteria and other eubacteria"@en . . . . . "Antibiotic 2233WP"@en . " "@en . . . . . . "For use in the treatment of acute gonorrheal urethritis and proctitis in the male and acute gonorrheal cervicitis and proctitis in the female when due to susceptible strains of Neisseria gonorrhoeae."@en . . "Rapidly and almost completely absorbed after intramuscular injection."@en . . . "1 to 3 hours in patients with normal renal function and 10 to 30 hours in patients with impaired renal function with a creatinine clearance < 20 mL per minute."@en .