. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "approved"@en . . . . . . . . . . . . . . . "(r)-(-)-menthol"@en . . "Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants."@en . . . . "Levomentholum"@en . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol"@en . . . . . . . . . "(1R,3R,4S)-(-)-Menthol"@en . . . . . . "(-)-(1R,3R,4S)-Menthol"@en . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "Tatsuo Higashiyama, Isao Sakata, \"Menthol glycoside, process for preparing the same and method for releasing menthol therefrom.\" U.S. Patent US4038270, issued December, 1972."@en . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "Levomenthol"@en . . . . . . . . . . . . "Menthol, DL: ORAL (LD50): Acute: 2900 mg/kg [Rat], 3100 mg/kg [Mouse]. DERMAL (LD50): Acute: 5001 mg/kg [Rabbit]."@en . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "Menthol primarily activates the cold-sensitive TRPM8 receptors in the skin. Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting Ca++ currents of neuronal membranes. It may also yield analgesic properties via kappa-opioid receptor agonism. "@en . " "@en . . . . . . . . . . . . . . . . . "(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol"@en . . . . . . . . . . . . . . . . . . "2216-51-5"@en . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "L-(-)-menthol"@en . . . . . . . . . . . "Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above. The main form of menthol occurring in nature is (-)-menthol, which is assigned the (1R,2S,5R) configuration. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation."@en . . . . . . . "Levomentol"@en . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "L-menthol"@en . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "(-)-menthol"@en . . . . . "Humans and other mammals"@en . . . . . "Menthol"@en . . . . . . . . . . . . . . . . . . . . . .