"Gastrointestinal symptoms including stomach and abdominal pain, vomiting, and diarrhea. Rash, hyperactivity, or drowsiness have also been observed in a small number of patients"@en . . . "Acidum clavulanicum"@en . . . . " "@en . . . . . . . . . . . . . . . . . "Clavulanic Acid"@en . . "Clavulansaeure"@en . . "(2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid"@en . . "Clavulanate"@en . . . . . . "Dennis Edward Clark, Shaukat Hussain Malik, Paul Gerard Butterly, Clive Elton Badman, Jeffrey David Haseler, \"Process for preparing potassium clavulanate in rossette form.\" U.S. Patent US5750685, issued April, 1978."@en . . "Clavulanate"@en . . . . . . . "Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase. [PubChem]"@en . . . . "Acide clavulanique"@en . . . . . . "1.0 hour"@en . . . "(Z)-(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid"@en . . . . . "approved"@en . . . "Enteric bacteria and other eubacteria"@en . . . . "Clavulanic acid competitively and irreversibly inhibits a wide variety of beta-lactamases, commonly found in microorganisms resistant to penicillins and cephalosporins. Binding and irreversibly inhibiting the beta-lactamase results in a restauration of the antimicrobial activity of beta-lactam antibiotics against lactamase-secreting-resistant bacteria. By inactivating beta-lactamase (the bacterial resistance protein), the accompanying penicillin/cephalosporin drugs may be made more potent as well."@en . . . . . . . . . . . . "75%"@en . . . . . . . . . . . . . . . . "For use with Amoxicillin, clavulanic acid is suitable for the treatment of infections with Staph. aureus and Bacteroides fragilis, or with beta-lactamase producing H. influenzae and E. coli."@en . . "Antibiotic mm 14151"@en . "Low (22 to 30%)"@en . . . . . . . "58001-44-8"@en . "MM 14151"@en . . "Acido clavulanico"@en . .