"51-34-3"@en . . . . . "Scopolamine"@en . . . "Transderm-scop"@en . . " "@en . . . . . . "Yang Guodong, \"Preparation and application of scopolamine and chlorpromazine as a drug-withdrawal agent.\" U.S. Patent US5543407, issued February, 1993."@en . . . "Humans and other mammals"@en . "scopine (\u2212)-tropate"@en . "Less than 10% of the total dose is excreted in the urine as parent and metabolites over 108 hours."@en . " "@en . . . . . "4.5 hours"@en . . . . "(1S,3S,5R,6R,7S)-6,7-Epoxytropan-3-yl (2S)-3-hydroxy-2-phenylpropanoate"@en . . "An alkaloid from Solanaceae, especially Datura metel L. and Scopola carniolica. Scopolamine and its quaternary derivatives act as antimuscarinics like atropine, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in urinary incontinence, in motion sickness, as an antispasmodic, and as a mydriatic and cycloplegic. [PubChem]"@en . "(-)-scopolamine"@en . . "approved"@en . . . . . . . . "Hyoscine"@en . . . . . . . . . . . . . . . . "Scopolamine"@en . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "# Putcha L, Cintron NM, Tsui J, Vanderploeg JM, Kramer WG: Pharmacokinetics and oral bioavailability of scopolamine in normal subjects. Pharm Res. 1989 Jun;6(6):481-5. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/2762223"@en . . . . . . . . . . . . "Scopine (-)-tropate"@en . . "Bioavailability is 10 - 50%"@en . . . . . . . . . "6,7-Epoxytropine tropate"@en . . . . . . . "alpha-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl ester"@en . . . . . . . . . . "Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system (specifically the vomiting center)."@en . . . . . "For the treatment of excessive salivation, colicky abdominal pain, bradycardia, sialorrhoea, diverticulitis, irritable bowel syndrome and motion sickness."@en . . . . . . . "(-)-hyoscine"@en . "6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate"@en . . . . . . .