"Esomeprazolum"@en . "(\u2212)-omeprazole"@en . . . . "Esomeprazole"@en . . . . . . . . . . . . . . . . . . "Esomeprazol"@en . . . . . . . . . "\u00C9som\u00E9prazole"@en . . . . . . "# Lind T, Rydberg L, Kyleback A, Jonsson A, Andersson T, Hasselgren G, Holmberg J, Rohss K: Esomeprazole provides improved acid control vs. omeprazole In patients with symptoms of gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2000 Jul;14(7):861-7. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/10886041"@en . . "A highly effective inhibitor of gastric acid secretion used in the therapy of stomach ulcers and zollinger-ellison syndrome. The drug inhibits the H(+)-K(+)-ATPase (H(+)-K(+)-exchanging ATPase) in the proton pump of gastric parietal cells. [PubChem]"@en . . . . . "90%"@en . . . . . . "Approximately 80% of the administered dose of esomeprazole is excreted as metabolites in urine and the remaining 20% is excreted in feces. "@en . . "1-1.5 hours"@en . "Take without regard to meals."@en . . . " "@en . . "investigational"@en . . . "(S)-(\u2212)-omeprazole"@en . "Humans and other mammals"@en . . . " "@en . . "Manne Reddy, \"Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof.\" U.S. Patent US20040167173, issued August 26, 2004."@en . . . . "97%"@en . . "(S)-omeprazole"@en . . . . . . . . . . . "approved"@en . . "Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H⁺/K⁺-ATPase in the gastric parietal cell. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity."@en . . . . . . . . . "161796-78-7"@en . . . "Perprazole"@en . . . . . . . . . . . . . . . . "* 16 L [healthy volunteers]"@en . "Blurred vision, confusion, drowsiness, dry mouth, flushing headache, nausea, rapid heartbeat, sweating"@en . . "For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use."@en .