"Azatadin"@en . . . . . "Take with food to reduce irritation."@en . " "@en . . "Azatadina"@en . "11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine"@en . . "Azatadine Maleate"@en . . " "@en . . . "Azatadinum"@en . . "Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release."@en . "Humans and other mammals"@en . . . "Azatadine"@en . "6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine"@en . . . . . . . . . . . . . . . . . . "3964-81-6"@en . . "Raymond E. Dagger, Linda A. Motyka, \"Process for preparing intermediates for azatidine.\" U.S. Patent US4954632, issued September 04, 1990."@en . . "Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release."@en . . . "Avoid alcohol."@en . . "# Zhang D, Hansen EB Jr, Deck J, Heinze TM, Sutherland JB, Cerniglia CE: Fungal biotransformation of the antihistamine azatadine by Cunninghamella elegans. Appl Environ Microbiol. 1996 Sep;62(9):3477-9. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/8795241 # Katelaris C: Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis. Asian Pac J Allergy Immunol. 1990 Dec;8(2):103-7. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/1982614 # Small P, Barrett D, Biskin N: Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation. Ann Allergy. 1990 Feb;64(2 Pt 1):129-31. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/1968324"@en . "Well absorbed after oral administration."@en . . . . . . . . . . . . "Azatadine"@en . "For the relief of the symptoms of upper respiratory mucosal congestion in perennial and allergic rhinitis, and for the relief of nasal congestion and eustachian t.b. congestion."@en . . . . "The oral LD₅₀ in mature rats and mice was greater than 1700 mg/kg and 600 mg/kg, respectively. Symptoms of overdose include clumsiness or unsteadiness, seizures, severe drowsiness, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath, shuffling walk, tic-like (jerky) movements of head and face, trembling and shaking of hands, and insomnia."@en . . "approved"@en .