. "approved"@en . "Pirenzepine"@en . . "Pirenzepinum"@en . . "Pirenz\u00E9pine"@en . . . . "11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one"@en . . . "Humans and other mammals"@en . " "@en . . . " "@en . . . . "Take 30 minutes before breakfast and at bedtime."@en . . . . "Pirenzepina"@en . "An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients. [PubChem]"@en . . . . . . . . . "Pirenzepine is a muscarinic receptor antagonist and binds to the muscarinic acetylcholine receptor. The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins."@en . . . . "# Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/16519089"@en . . . . . . . "For the treatment of peptic ulcer, gastric ulcer, and duodenal ulcer."@en . . . "Pirenzepin"@en . . . "28797-61-7"@en . . . .