. . "51-74-1"@en . . . "Histamine phosphate is indicated as a diagnostic aid for evaluation of gastric acid secretory function."@en . . "Readily absorbed after parenteral administration"@en . . "4-(2-Aminoethyl)imidazole di-acid phosphate"@en . . . . . "Histaminum"@en . . . . . . . . "LD₅₀=807 mg/kg (mouse, oral). Side effects can lead to hypertension, hypotension, headache, dizziness, nervousness and tachycardia. Large overdoses can lead to seizures."@en . . "Histamine dihydrogen phosphate"@en . . . . "approved"@en . . . . . . . . . . . . . "Histamine acid phosphate"@en . . . "Histamine Phosphate"@en . . "Histamine diphosphate"@en . . . . " "@en . "Histamine phosphate (1:2)"@en . . . . . "Histamine stimulates gastric gland secretion, causing an increased secretion of gastric juice of high acidity. This action is probably due mainly to a direct action on parietal and chief gland cells."@en . "Humans and other mammals"@en . . "Histamine biphosphate"@en . . "Histamine acts directly on the blood vessels to dilate arteries and capillaries; this action is mediated by both H 1- and H 2-receptors. Capillary dilatation may produce flushing of the face, a decrease in systemic blood pressure, and gastric gland secretion, causing an increased secretion of gastric juice of high acidity. Increased capillary permeability accompanies capillary dilatation, producing an outward passage of plasma protein and fluid into the extracellular spaces, an increase in lymph flow and protein content, and the formation of edema. In addition, histamine has a direct stimulant action on smooth muscle, producing contraction if H 1-receptors are activated, or mostly relaxation if H 2-receptors are activated. Also in humans, the stimulant effect of histamine may cause contraction of the intestinal muscle. However, little effect is noticed on the uterus, bladder, or gallbladder. Histamine has some stimulant effect on duodenal, salivary, pancreatic, bronchial, and lacrimal glands. Histamine also can bind to H3 and H4 receptors which are involved in the CNS/PNS neurotransmitter release and immune system chemotaxis, respectively."@en . . . . "4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)"@en .