. . . . . . . . . . . . . . . . . "# Miller AL: Dimercaptosuccinic acid (DMSA), a non-toxic, water-soluble treatment for heavy metal toxicity. Altern Med Rev. 1998 Jun;3(3):199-207. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/9630737 # Aaseth J, Jacobsen D, Andersen O, Wickstrom E: Treatment of mercury and lead poisonings with dimercaptosuccinic acid and sodium dimercaptopropanesulfonate. A review. Analyst. 1995 Mar;120(3):853-4. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/7741240 # Mann KV, Travers JD: Succimer, an oral lead chelator. Clin Pharm. 1991 Dec;10(12):914-22. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/1663439"@en . . . "Oral LD₅₀ in mice is over 5011 mg/kg. Doses of 2300 mg/kg in the rat and 2400 mg/kg in the mouse produced ataxia, convulsions, labored respiration and frequently death. No case of overdosage has been reported in humans. Limited data indicate that succimer is dialyzable."@en . . . . "Meso-2,3-dimercaptosuccinic acid"@en . "304-55-2"@en . "Succimer is a heavy metal chelator. It binds with high specificity to ions of lead in the blood to form a water-soluble complex that is subsequently excreted by the kidneys. Succimer can also chelate mercury, cadmium, and arsenic in this manner."@en . . "Unabsorbed drug is excreted primarily in feces and absorbed drug is excreted primarily in the urine as metabolites."@en . "approved"@en . . . . . . . . "Dimercaptosuccinic acid"@en . . . . "Chemet"@en . . "Meso-dimercaptosuccinic acid"@en . . . "For the treatment of lead poisoning in pediatric patients with blood lead levels above 45 µg/dL. May also be used to treat mercury or arsenic poisoning."@en . "Humans and other mammals"@en . . . . . . . . . . . . "Rapid but variable."@en . . " "@en . . . . "A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them. [PubChem]"@en . "48 hours"@en . . . "DMSA"@en . . "Succimer"@en .