. . "Thiethylperazinum"@en . "2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine"@en . "Thiethylperazine is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors. Thiethylperazine's antipsychotic effect is due to antagonism at dopamine and serotonin type 2 receptors, with greater activity at serotonin 5-HT2 receptors than at dopamine type-2 receptors. This may explain the lack of extrapyramidal effects. Thiethylperazine does not appear to block dopamine within the tubero-infundibular tract, explaining the lower incidence of hyperprolactinemia than with typical antipsychotic agents or risperidone. Antagonism at muscarinic receptors, H1-receptors, and alpha(1)-receptors also occurs with thiethylperazine."@en . . "1420-55-9"@en . . . . . . . . . "# Maurer H, Pfleger K: Identification of phenothiazine antihistamines and their metabolites in urine. Arch Toxicol. 1988;62(2-3):185-91. \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/2904251"@en . . "60%"@en . . . "Humans and other mammals"@en . . . . . "Thiethylperazin"@en . . " "@en . . . . . . . "Tietilperazina"@en . . "A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)"@en . . . . . . . "Thiethylperazine"@en . . "Thi\u00E9thylp\u00E9razine"@en . "Manifestations of acute overdosage of TORECAN (thiethylperazine) can be expected to reflect the CNS effects of the drug and include extrapyramidal symptoms (E.P.S), confusion and convulsions with reduced or absent reflexes, respiratory depression and hypotension."@en . " "@en . "Thiethylperazine is eliminated in the urine. "@en . "withdrawn"@en . . "Thiethylperazine"@en . . . . . . . . . . . "For the treatment or relief of nausea and vomiting."@en . . "Norzine"@en . .