. . . . . "A phospholipid-interacting antimalarial drug (antimalarials). It is very effective against plasmodium falciparum with very few side effects. [PubChem]"@en . . . "* 20 L/kg [healthy adults]"@en . . "* 30 mL/min"@en . "\"DrugSyn.org\":http://www.drugsyn.org/Mefloquine.htm"@en . "Mefloquinum"@en . . "There is evidence that mefloquine is excreted mainly in the bile and feces. Urinary excretion of unchanged mefloquine and its main metabolite under steady-state condition accounted for about 9% and 4% of the dose, respectively."@en . . "Well absorbed from the gastrointestinal tract. The presence of food significantly enhances the rate and extent of absorption."@en . . . . . . "[(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol"@en . "Avoid alcohol."@en . . . "53230-10-7"@en . . . . . . . . . . . . "Oral, rat: LD₅₀ = 880 mg/kg. Symptoms of overdose include nausea, vomiting, and weight loss."@en . . . "For the treatment of mild to moderate acute malaria caused by Mefloquineuine-susceptible strains of Plasmodium falciparum (both chloroquine-susceptible and resistant strains) or by Plasmodium vivax. Also for the prophylaxis of Plasmodium falciparum and Plasmodium vivax malaria infections, including prophylaxis of chloroquine-resistant strains of Plasmodium falciparum."@en . "Mefloquine"@en . . . . "Mefloquina"@en . "alpha-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol"@en . "Take with food."@en . . . "Mefloquin"@en . . . . "Mefloquine has been found to produce swelling of the Plasmodium falciparum food vacuoles. It may act by forming toxic complexes with free heme that damage membranes and interact with other plasmodial components."@en . . "Mefloquine"@en . . . . . . "2 to 4 weeks"@en . "98%"@en . . . . . . . . . . . . "approved"@en . . . . . . . "Plasmodium"@en . . . . . . " "@en . . "M\u00E9floquine"@en . . . . " "@en . "Take with a full glass of water."@en .