"Sulfisoxazole"@en . . "5-(P-Aminobenzenesulphonamido)-3,4-dimethylisoxazole"@en . "5-(P-Aminobenzenesulfonamido)-3,4-dimethylisoxazole"@en . "N'-(3,4)dimethylisoxazol-5-yl-sulphanilamide"@en . . . "Sulphafurazole"@en . "3,4-Dimethylisoxazole-5-sulfanilamide"@en . " "@en . "Sulfisoxazol"@en . "Sulfaisoxazole"@en . "3,4-Dimethyl-5-sulphonamidoisoxazole"@en . "Sulfafurazole"@en . "Sulfadimethylisoxazole"@en . "Sulfisoxasole"@en . "Sulfafurazol"@en . . . . . "Sulfasoxazole"@en . . . " "@en . . "Sulphisoxazol"@en . "Sulphadimethylisoxazole"@en . "Sulfisoxazole is a competitive inhibitor of the enzyme dihydropteroate synthetase. It inhibits bacterial synthesis of dihydrofolic acid by preventing the condensation of the pteridine with para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid."@en . . "The mean urinary excretion recovery following oral administration of sulfisoxazole is 97% within 48 hours, of which 52% is intact drug, with the remaining as the N4-acetylated metabolite. It is excreted in human milk."@en . "N(1)-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide"@en . "Sulphaisoxazole"@en . "approved"@en . "Sulfafurazolum"@en . . . "4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide"@en . . "3,4-Dimethylisoxazole-5-sulphanilamide"@en . . . "3,4-Dimethyl-5-sulfanilamidoisoxazole"@en . . . . . . . . . . . . . . . . . . . . . "Enteric bacteria and other eubacteria"@en . . . . . . . . . . . . . "N(1)-(3,4-Dimethyl-5-isoxazolyl)sulphanilamide"@en . . . "LD₅₀=6800 mg/kg (Orally in mice)"@en . . . . . . . . . . . . . . . "Sulphofurazole"@en . "Sulfofurazole"@en . . . . "4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide"@en . "5-Sulphanilamido-3,4-dimethyl-isoxazole"@en . "5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole"@en . "127-69-5"@en . . . . "For the treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections."@en . . . . . "5-Sulfanilamido-3,4-dimethylisoxazole"@en . "3,4-Dimethyl-5-sulphanilamidoisoxazole"@en . . . . . "Sulphafurazol"@en . . . . . "Sulfisonazole"@en . . . . . . . "3,4-Dimethyl-5-sulfonamidoisoxazole"@en . "A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms. [PubChem]"@en .