. . "Tetrahydrofolate is transported across cells by receptor-mediated endocytosis where it is needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate."@en . . . . "For nutritional supplementation, also for treating dietary shortage or imbalance."@en . . . "(6S)-Tetrahydrofolate"@en . . . . "Attilio Melera, Fabrizio Marazza, \"Process for the preparation of alkaline earth metal salts of (6R)-N(10)-formyl-5,6,7,8-tetrahydrofolic acid.\" U.S. Patent US5332815, issued May, 1954."@en . "THF"@en . . . . . . . . . . . . "(6S)-Tetrahydrofolic acid"@en . "Tetrahydrofolic acid"@en . . . "approved"@en . " "@en . . "135-16-0"@en . . . . "Tetrahydrofolic acid"@en . "nutraceutical"@en . "5,6,7,8-tetrahydrofolate"@en . . . . "Humans and other mammals"@en . . . "5,6,7,8-tetrahydrofolic acid"@en . . . "(6S)-THFA"@en . "tetrahydrofolate"@en . "Tetrahydrofolic acid is a folic acid derivative. It is produced from dihydrofolic acid by dihydrofolate reductase. It is converted into 5,10-methylenetetrahydrofolate by serine hydroxymethyltransferase. It is a coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids. It acts as a donor of a group with one carbon atom. It gets this carbon atom by sequestering formaldehyde produced in other processes."@en . . . . . . .