. "2011-01-26+01:00"^^ . "V\u00FDzkumn\u00FD z\u00E1m\u011Br je vynikaj\u00EDc\u00EDm p\u0159\u00EDkladem c\u00EDlen\u00E9 podpory \u0161pi\u010Dkov\u00FDch laborato\u0159\u00ED. T\u00FDmy prof. Star\u00E9ho m\u011Bly sv\u00E9 jasn\u00E9 sm\u011Brov\u00E1n\u00ED ji\u017E v dob\u011B formulov\u00E1n\u00ED v\u00FDzkumn\u00E9ho z\u00E1m\u011Bru, ale finan\u010Dn\u00ED podpora stabilizovala mlad\u00E9 v\u011Bdce a umo\u017Enila roz\u0161\u00ED\u0159it paletu jedine\u010Dn\u00FDch diagnostick\u00FDch metod. Je opravdu jedine\u010Dn\u00E9, \u017Ee evidentn\u00ED pokrok v diagnostice se bezprost\u0159edn\u011B odrazil v podstatn\u00E9m n\u00E1r\u016Fstu \u00FAsp\u011B\u0161nosti l\u00E9\u010Dby. Zcela mi"@cs . "0"^^ . . . "Tumours in children patients differ from those in adults, not only in the range of the various types of malignities and their biology, but also in the therapies used and the outcomes thereof. Today, paediatric haematology and oncology is thereforeconsidered an independent scientific and medicinal discipline. The dissimilarity of the biological properties of the malignities in childhood and adulthood, as well as the difference between the respective treatmentprocedures and/or preferences can be demonstrated by the fact that, the few negligible exceptions notwithstanding, children patients are treated using different protocols from those employed in adults (e.g. acute leukaemias, lymphomes)."@en . "2005-01-01+01:00"^^ . . . . . "1"^^ . "The Molecular Basis of Childhood Malignancies and Therapeutic Applications"@en . "2011-12-31+01:00"^^ . "138"^^ . "2012-08-17+02:00"^^ . . . . . . . "The research project represents an unique example of the well-focused support of very good laboratories. Professor Stary teams had a clear orientation at the time of research project formulation but the finantial support stabilized zoung researchers and increased number of diagnostic methods. It is an unique example when the substantial diagnostic progress has instantly reflected in the successful"@en . "0"^^ . . "Molekul\u00E1rn\u00ED z\u00E1klady d\u011Btsk\u00FDch n\u00E1dorov\u00FDch onemocn\u011Bn\u00ED a l\u00E9\u010Debn\u00E9 aplikace" . "Childhood Malignancies; Tumours; children patients"@en . "138"^^ . . . . "N\u00E1dorov\u00E1 onemocn\u011Bn\u00ED jsou druhou nej\u010Dast\u011Bj\u0161\u00ED p\u0159\u00ED\u010Dinou \u00FAmrt\u00ED v d\u011Btsk\u00E9m v\u011Bku. C\u00EDlem tohoto projektu je dosa\u017Een\u00ED pokroku v pozn\u00E1n\u00ED etiologie a patogenese d\u011Btsk\u00FDch malign\u00EDch n\u00E1dorov\u00FDch onemocn\u011Bn\u00ED a p\u0159enesen\u00ED t\u011Bchto v\u00FDsledk\u016F do diagnostick\u00E9 a l\u00E9\u010Debn\u00E9 praxe.Projekt funk\u010Dn\u011B propoj\u00ED l\u00E9\u010Debnou a v\u00FDzkumnou z\u00E1kladnu v oboru d\u011Btsk\u00E9 onkologie na Universit\u011B Karlov\u011B. P\u0159edm\u011Btem komplexn\u00EDho v\u00FDzkumu budou d\u011Btsk\u00E9 leukemie a nej\u010Dast\u011Bj\u0161\u00ED typy solidn\u00EDch n\u00E1dor\u016F d\u011Btsk\u00E9ho v\u011Bku.C\u00EDlem projektu je zaveden\u00ED nov\u00FDch imunologick\u00FDch a molekul\u00E1rn\u011B genetick\u00FDch vy\u0161et\u0159ovac\u00EDch metod, vyhled\u00E1v\u00E1n\u00ED a zkoum\u00E1n\u00ED nov\u00FDch marker\u016F a zkoum\u00E1n\u00ED funkce a poruch sign\u00E1ln\u00EDch drah, onkogen\u016F a bun\u011B\u010Dn\u00FDch enzymatick\u00FDch pochod\u016F u d\u011Btsk\u00FDch n\u00E1dorov\u00FDch onemocn\u011Bn\u00ED." . . .