"Deriv\u00E1ty tamoxifenu \u00FA\u010Dinn\u00E9 proti n\u00E1dor\u016Fm, zejm\u00E9na s vy\u0161\u0161\u00ED hladinou proteinu HER2"@cs . "Neu\u017Eil, Ji\u0159\u00ED" . . "P(ED1.1.00/02.0109), Z(AV0Z50520701)" . . "[249BBF16382D]" . "2"^^ . "RIV/86652036:_____/14:00431988!RIV15-AV0-86652036" . "1"^^ . . . "Mitochondri\u00E1ln\u011B c\u00EDlen\u00E9 E a/nebo Z izomery alkyltrifenylfosfoniov\u00FDch deriv\u00E1t\u016F tamoxifenu nebo jejich sm\u011Bs obecn\u00E9ho vzorce I, kde n=8 a\u017E 12 a X=Br, I, mesyl, kter\u00E9 se pou\u017E\u00EDvaj\u00ED k l\u00E9\u010Db\u011B n\u00E1dor\u016F, zejm\u00E9na s vy\u0161\u0161\u00ED hladinou proteinu HER2 a zp\u016Fsob jejich p\u0159\u00EDpravy. L\u00E9\u010Divo k l\u00E9\u010Db\u011B neoplastick\u00FDch chorob podle vyn\u00E1lezu obsahuje nejm\u00E9n\u011B jeden E a/nebo Z izomer alkyltrifenylfosfoniov\u00FDch deriv\u00E1t\u016F tamoxifenu obecn\u00E9ho vzorce I."@cs . . . . . . "Analogues of tamoxifen efficient in particular against Her2-high tumours"@en . . "Mitochondri\u00E1ln\u011B c\u00EDlen\u00E9 E a/nebo Z izomery alkyltrifenylfosfoniov\u00FDch deriv\u00E1t\u016F tamoxifenu nebo jejich sm\u011Bs obecn\u00E9ho vzorce I, kde n=8 a\u017E 12 a X=Br, I, mesyl, kter\u00E9 se pou\u017E\u00EDvaj\u00ED k l\u00E9\u010Db\u011B n\u00E1dor\u016F, zejm\u00E9na s vy\u0161\u0161\u00ED hladinou proteinu HER2 a zp\u016Fsob jejich p\u0159\u00EDpravy. L\u00E9\u010Divo k l\u00E9\u010Db\u011B neoplastick\u00FDch chorob podle vyn\u00E1lezu obsahuje nejm\u00E9n\u011B jeden E a/nebo Z izomer alkyltrifenylfosfoniov\u00FDch deriv\u00E1t\u016F tamoxifenu obecn\u00E9ho vzorce I." . . "Prague" . "2014-05-21+02:00"^^ . . "mitochondria; tamoxifen; breast cancer"@en . . "Deriv\u00E1ty tamoxifenu \u00FA\u010Dinn\u00E9 proti n\u00E1dor\u016Fm, zejm\u00E9na s vy\u0161\u0161\u00ED hladinou proteinu HER2"@cs . "\u00DA\u0159ad pr\u016Fmyslov\u00E9ho vlastnictv\u00ED" . . "RIV/86652036:_____/14:00431988" . . "Mitochondrially targeted E and/or Z isomers of alkyltriphenylphosphonium derivatives of tamoxifen or their mixtures of the general formula I, where n = 8 till 12 and X = Br, I or mesyl, which are used for therapy of tumours, in particular those with high level of HER2, and the method of their preparation. The therapeutic agent for neoplastic diseases according to the invention contains at least one E and/or Z isomer of triphenylphosphonium derivative of tamoxifen of the general formula I."@en . "Deriv\u00E1ty tamoxifenu \u00FA\u010Dinn\u00E9 proti n\u00E1dor\u016Fm, zejm\u00E9na s vy\u0161\u0161\u00ED hladinou proteinu HER2" . . . "Deriv\u00E1ty tamoxifenu \u00FA\u010Dinn\u00E9 proti n\u00E1dor\u016Fm, zejm\u00E9na s vy\u0161\u0161\u00ED hladinou proteinu HER2" . . . . . . "Analogues of tamoxifen efficient in particular against Her2-high tumours"@en . "304553" . "Smart Brain s. r. o., Praha 4, CZ - Biotechnologick\u00FD \u00FAstav AV \u010CR, v. v. i., Praha 4, CZ - Ji\u0159\u00ED Neu\u017Eil prof. Ing., CSc., Praha 4, CZ" . "10342" . . "\u0160tursa, J." .