. . . . "Association of MiR-126 with Soluble Mesothelin-Related Peptides, a Marker for Malignant Mesothelioma"@en . "6" . "Improved detection methods for diagnosis of malignant mesothelioma (MM) are essential for detection and treatment. miRNAs isolated from fresh-frozen biopsies of MM patients were tested for the expression of 88 types of miRNA involved in cancerogenesis. Three significantly downregulated miRNAs were assayed in cancerous tissue and adjacent non-cancerous tissue sample pairs collected from 27 formalin-fixed, paraffin-embedded MM tissues by quantitative RT-PCR. Only miR-126 remained downregulated in the malignant tissues. The performance of the selected miR-126 as biomarker was evaluated in serum samples of asbestos-exposed subjects and MM patients and compared with controls. MiR-126 was not affected by asbestos exposure, whereas it was found associated with VEGF serum levels. Levels of miR-126 in serum, and its levels in patients' serum in association with a specific marker of MM, SMRPs, correlate with subjects at high risk to develop MM." . . "Association of MiR-126 with Soluble Mesothelin-Related Peptides, a Marker for Malignant Mesothelioma" . "1932-6203" . "Tomasetti, M." . "Sartini, D." . "RIV/86652036:_____/11:00369516!RIV12-AV0-86652036" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "Association of MiR-126 with Soluble Mesothelin-Related Peptides, a Marker for Malignant Mesothelioma"@en . "9"^^ . "Amati, M." . "Sabbatini, A." . . . "Ranaldi, R." . "Gasparini, S." . "Improved detection methods for diagnosis of malignant mesothelioma (MM) are essential for detection and treatment. miRNAs isolated from fresh-frozen biopsies of MM patients were tested for the expression of 88 types of miRNA involved in cancerogenesis. Three significantly downregulated miRNAs were assayed in cancerous tissue and adjacent non-cancerous tissue sample pairs collected from 27 formalin-fixed, paraffin-embedded MM tissues by quantitative RT-PCR. Only miR-126 remained downregulated in the malignant tissues. The performance of the selected miR-126 as biomarker was evaluated in serum samples of asbestos-exposed subjects and MM patients and compared with controls. MiR-126 was not affected by asbestos exposure, whereas it was found associated with VEGF serum levels. Levels of miR-126 in serum, and its levels in patients' serum in association with a specific marker of MM, SMRPs, correlate with subjects at high risk to develop MM."@en . . "4" . . . . "[06D3895CF5B3]" . "Association of MiR-126 with Soluble Mesothelin-Related Peptides, a Marker for Malignant Mesothelioma" . "Emanuelli, M." . "Pozzi, V." . "187336" . . "P(GA204/08/0811), Z(AV0Z50520701)" . "PLoS ONE" . "Bracci, M." . "Strafella, E." . . . "Staffolani, S." . "Carbonari, D." . "1"^^ . "Santarelli, L." . "Neu\u017Eil, Ji\u0159\u00ED" . "RIV/86652036:_____/11:00369516" . "Malignant pleural mesothelioma; microRNAs; soluble mesothelin-related peptides"@en . "000289058300007" . . "Pignotti, E." . "16"^^ . . "10.1371/journal.pone.0018232" . . "Mazzanti, P." . .