"S" . . . "Preparation of 1-monoacylglycerols by the reation of fatty acids with glycidol"@en . "Preparation of 1-monoacylglycerols by the reation of fatty acids with glycidol" . . "Preparation of 1-monoacylglycerols by the reation of fatty acids with glycidol"@en . "Preparation of 1-monoacylglycerols by the reation of fatty acids with glycidol" . "Preparation; 1-monoacylglycerols; reation"@en . "Monoacylglycerols belong among the most important esters of glycerol and fatty acids that are widely used in the food industry as emulsifiers. Due to their antimicrobial properties they are applied in the medicine and pharmacy for the prevention and treatment of various diseases. Moreover, they serve for the facilitation of pharmaceuticals and vitamins administration. Glycerolysis is the most frequent industrial process used for their manufacture. However, this is relatively energy demanding. Recently, the enzymatic ways using lipases have been intensively studied because of milder reaction conditions. Especially alcoholysis of triacylglycerols with glycerol or esterification of fatty acids are exploited. The perspective method of monoacylglycerols preparation is the fatty acid addition to glycidol by the nucleophilic opening of epoxy ring. The optimum reaction conditions, i.e. the reaction temperature, time, molar ratio of input components and a suitable catalyst amount were determined in this doct"@en . "1"^^ . "Monoacylglycerols belong among the most important esters of glycerol and fatty acids that are widely used in the food industry as emulsifiers. Due to their antimicrobial properties they are applied in the medicine and pharmacy for the prevention and treatment of various diseases. Moreover, they serve for the facilitation of pharmaceuticals and vitamins administration. Glycerolysis is the most frequent industrial process used for their manufacture. However, this is relatively energy demanding. Recently, the enzymatic ways using lipases have been intensively studied because of milder reaction conditions. Especially alcoholysis of triacylglycerols with glycerol or esterification of fatty acids are exploited. The perspective method of monoacylglycerols preparation is the fatty acid addition to glycidol by the nucleophilic opening of epoxy ring. The optimum reaction conditions, i.e. the reaction temperature, time, molar ratio of input components and a suitable catalyst amount were determined in this doct" . . "RIV/70883521:28110/06:63505067!RIV07-MSM-28110___" . . "28110" . "1"^^ . "494265" . "RIV/70883521:28110/06:63505067" . . . . . . . "[4953723F0B03]" . "P\u0159\u00EDprava 1-monoacylglycerol\u016F reakc\u00ED mastn\u00FDch kyselin s glycidolem"@cs . "Monoacylglyceroly pat\u0159\u00ED mezi nejv\u00FDznamn\u011Bj\u0161\u00ED estery glycerolu a mastn\u00FDch kyselin, kter\u00E9 jsou jako emulg\u00E1tory \u0161iroce vyu\u017E\u00EDv\u00E1ny v potravin\u00E1\u0159sk\u00E9m pr\u016Fmyslu. Pro sv\u00E9 antimikrobi\u00E1ln\u00ED vlastnosti nach\u00E1zej\u00ED uplatn\u011Bn\u00ED tak\u00E9 v medic\u00EDn\u011B a farmacii pro prevenci a l\u00E9\u010Dbu r\u016Fzn\u00FDch onemocn\u011Bn\u00ED. Mimo jin\u00E9 slou\u017E\u00ED k usnadn\u011Bn\u00ED pod\u00E1v\u00E1n\u00ED l\u00E9\u010Div a vitam\u00EDn\u016F. V pr\u016Fmyslu nej\u010Dast\u011Bji vyu\u017E\u00EDvan\u00FD zp\u016Fsob jejich v\u00FDroby - glycerol\u00FDza - je pom\u011Brn\u011B energeticky n\u00E1ro\u010Dn\u00FD. V posledn\u00ED dob\u011B jsou d\u00EDky m\u00EDrn\u011Bj\u0161\u00EDm reak\u010Dn\u00EDm podm\u00EDnk\u00E1m intenzivn\u011B studov\u00E1ny enzymatick\u00E9 zp\u016Fsoby v\u00FDroby - za p\u0159\u00EDtomnosti lip\u00E1z - vzhledem k jejich ekologi\u010Dnosti. Jedn\u00E1 se p\u0159edev\u0161\u00EDm o alkohol\u00FDzu triacylglycerol\u016F s glycerolem, \u010Di esterifikaci mastn\u00FDch kyselin. Velmi perspektivn\u00EDm zp\u016Fsobem p\u0159\u00EDpravy monoacylglycerol\u016F je adice mastn\u00E9 kyseliny na glycidol nukleofiln\u00EDm otev\u0159en\u00EDm epoxidov\u00E9ho kruhu. P\u0159edkl\u00E1dan\u00E1 doktorsk\u00E1 pr\u00E1ce se zab\u00FDv\u00E1 stanoven\u00EDm optim\u00E1ln\u00EDch reak\u010Dn\u00EDch podm\u00EDnek, tj. reak\u010Dn\u00ED teploty, \u010Dasu, mol\u00E1rn\u00EDho pom\u011Bru l\u00E1tek vstupuj\u00EDc\u00EDch do reakce a v\u00FDb\u011Brem vhodn\u00E9ho typu katalyz\u00E1tor"@cs . "Bob\u00E1lov\u00E1, Jana" . . . "P\u0159\u00EDprava 1-monoacylglycerol\u016F reakc\u00ED mastn\u00FDch kyselin s glycidolem"@cs . .