. "2012-05-29+02:00"^^ . "4"^^ . "bloodstream; photosensitivity; , diseased cells; , lipophilic substances"@en . "2"^^ . "Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds"@en . . "Hydrophobic substances (phthalocy anines) tend to aggregate in hydrophilic environment (bloodstream) and as a result they can lose their unique properties (photosensitivity). This can be overcome by encapsulating the substances into a drug delivery carrier, e.g. spheres from a biocompatible and biodegradable polymer. In thispaper polycaprolactone (PCL) spheres were synthetized by electrospraying, a method for preparation of polymeric micro- and nanospheres by high voltage application to a jet of polymer solution. The concentration dependence of PCL solution was investigated in the range of 1 % PCL solution to 10 % PCL solution. The samples were analyzed by scanning electron microscopy (SEM). The 7 % and 8 % PCL solutions seem to be the best concentration for PCL spheres preparation." . . . "Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds" . . . "Vocetkov\u00E1, Karol\u00EDna" . "172984" . . "P(EE.2.3.20.0092)" . "978-80-01-05119-1" . "Prague" . . "Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds" . "RIV/68407700:21460/12:00202770" . "Kladno" . . . . . . "Hydrophobic substances (phthalocy anines) tend to aggregate in hydrophilic environment (bloodstream) and as a result they can lose their unique properties (photosensitivity). This can be overcome by encapsulating the substances into a drug delivery carrier, e.g. spheres from a biocompatible and biodegradable polymer. In thispaper polycaprolactone (PCL) spheres were synthetized by electrospraying, a method for preparation of polymeric micro- and nanospheres by high voltage application to a jet of polymer solution. The concentration dependence of PCL solution was investigated in the range of 1 % PCL solution to 10 % PCL solution. The samples were analyzed by scanning electron microscopy (SEM). The 7 % and 8 % PCL solutions seem to be the best concentration for PCL spheres preparation."@en . "21460" . . . . . "RIV/68407700:21460/12:00202770!RIV13-MSM-21460___" . . "Jaro\u0161\u00EDkov\u00E1, Ta\u0165\u00E1na" . "M\u00ED\u010Dkov\u00E1, A." . "Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds"@en . . "[8A87D3EF66F4]" . "Buzgov, M." . "\u010Cesk\u00E9 vysok\u00E9 u\u010Den\u00ED technick\u00E9 v Praze" . "4"^^ . . "Instuments and Methods for Biology and Medicine 2012" .