. "188640" . . "Boron Doped Nanocrystalline Diamond Films for Biosensing Applications" . "Boron Doped Nanocrystalline Diamond Films for Biosensing Applications"@en . . "Krucky, J." . . "5" . "Vl\u010Dkov\u00E1, Marie" . "[0D63AD9EB04A]" . "CZ - \u010Cesk\u00E1 republika" . "Boron Doped Nanocrystalline Diamond Films for Biosensing Applications"@en . . "2011" . "1210-2709" . "RIV/68407700:21460/11:00183657" . "With the rise of antibiotic resistance of pathogenic bacteria there is an increased demand for monitoring the functionality of bacteria membranes, the disruption of which can be induced by peptide-lipid interactions. In this work we attempt to construct and disrupt supported lipid membranes (SLB) on boron doped nanocrystalline diamond (B-NCD). Electrochemical Impedance Spectroscopy (EIS) was used to study in situ changes related to lipid membrane formation and disruption by peptide-induced interactions. The observed impedance changes were minimal for oxidized B-NCD samples, but were still detectable in the low frequency part of the spectra. The sensitivity for the detection of membrane formation and disruption was significantly higher for hydrogenated B-NCD surfaces. Data modeling indicates large changes in the electrical charge when an electrical double layer is formed at the B-NCD/SLB interface, governed by ion absorption. By contrast, for oxidized B-NCD surfaces"@en . "3"^^ . . . . . . . "biosensor; nanocrystalline diamond; electrochemical impedance spectroscopy"@en . . "Acta Polytechnica" . . . "2"^^ . "21460" . . . . . "Petr\u00E1k, V\u00E1clav" . "With the rise of antibiotic resistance of pathogenic bacteria there is an increased demand for monitoring the functionality of bacteria membranes, the disruption of which can be induced by peptide-lipid interactions. In this work we attempt to construct and disrupt supported lipid membranes (SLB) on boron doped nanocrystalline diamond (B-NCD). Electrochemical Impedance Spectroscopy (EIS) was used to study in situ changes related to lipid membrane formation and disruption by peptide-induced interactions. The observed impedance changes were minimal for oxidized B-NCD samples, but were still detectable in the low frequency part of the spectra. The sensitivity for the detection of membrane formation and disruption was significantly higher for hydrogenated B-NCD surfaces. Data modeling indicates large changes in the electrical charge when an electrical double layer is formed at the B-NCD/SLB interface, governed by ion absorption. By contrast, for oxidized B-NCD surfaces" . "P(LD11078), S, Z(MSM6840770012)" . . "RIV/68407700:21460/11:00183657!RIV12-MSM-21460___" . . "5"^^ . "Boron Doped Nanocrystalline Diamond Films for Biosensing Applications" .