. . "Hu\u0148ka, Petr" . . . "2"^^ . "Purpose Parallelizing Cannulas of Obese Patiens on ECMO Support"@en . . "RIV/68407700:21230/11:00190112!RIV13-MSM-21230___" . "Purpose Parallelizing Cannulas of Obese Patiens on ECMO Support" . . "ECMO; Canullas; Obese"@en . . . . . "Je\u017Eek, Filip" . . . "21230" . "2"^^ . . "Purpose Parallelizing Cannulas of Obese Patiens on ECMO Support"@en . "Objectives: Obese patients have a significantly higher risk of stroke complications during ECMO support. That risk is connected with advanced state of atherosclerosis. Larger patients need higher perfusion flow, which needs high pressure in the ECMO set. Then, the flow from outflow cannula is of high energy, which could result in releasing of atherosclerotic plaques. Methods: The best way to lower the systemic pressure is to lower the resistance of junction between patient and the ECMO system. This resistance is formed on inflow/outflow cannula. Inspired from electrical analogies, we tried to lower the pressure by parallelizing the inflow and outflow cannulas. We designed a simple model to illustrate this approach. Results: In ideal cases, the pressure is two times lower with paralel connection than with standard connection. This positively influences the blood energy in outflow cannula and lowers the risk of releasing atherosclerotic plaques. We are aware of complications associated with higher surface area and implementation of other cannulas, but we are convinced that the benefits are for obese patients more important. Conclusions: Parallelizing the inflow and outflow cannulas is a promising way to lower risk of stroke complications during ECMO support of obese patients." . "Purpose Parallelizing Cannulas of Obese Patiens on ECMO Support" . . . "S" . "[38BCDB2091FD]" . . "Objectives: Obese patients have a significantly higher risk of stroke complications during ECMO support. That risk is connected with advanced state of atherosclerosis. Larger patients need higher perfusion flow, which needs high pressure in the ECMO set. Then, the flow from outflow cannula is of high energy, which could result in releasing of atherosclerotic plaques. Methods: The best way to lower the systemic pressure is to lower the resistance of junction between patient and the ECMO system. This resistance is formed on inflow/outflow cannula. Inspired from electrical analogies, we tried to lower the pressure by parallelizing the inflow and outflow cannulas. We designed a simple model to illustrate this approach. Results: In ideal cases, the pressure is two times lower with paralel connection than with standard connection. This positively influences the blood energy in outflow cannula and lowers the risk of releasing atherosclerotic plaques. We are aware of complications associated with higher surface area and implementation of other cannulas, but we are convinced that the benefits are for obese patients more important. Conclusions: Parallelizing the inflow and outflow cannulas is a promising way to lower risk of stroke complications during ECMO support of obese patients."@en . "225291" . "RIV/68407700:21230/11:00190112" .