"1"^^ . "\u010Cl\u00E1nek obsahuje osobn\u00ED pohled autora na v\u011Bdeckou a spole\u010Denskou atmosf\u00E9ru b\u00FDval\u00E9ho \u010Ceskoslovenska. Zab\u00FDv\u00E1 se obdob\u00EDm vzestupu Ha\u0161kovy imunologick\u00E9 \u0161koly a aplikac\u00ED imunologick\u00E9 tolerance na hetero-p\u0159enos viru Rousova sarkomu (RSV). To umo\u017Enilo vytvo\u0159it nov\u00FD model sav\u010D\u00EDch bun\u011Bk transformovan\u00FDch RSV (virogenn\u00EDch XC bun\u011Bk), kde neinfek\u010Dn\u00ED virov\u00FD genom je p\u0159\u00EDtomen jako nov\u00E1 genetick\u00E1 informace (provirus). RSV bylo v\u0161ak mo\u017Eno z\u00EDskat ze sav\u010D\u00EDch nepermisivn\u00EDch bun\u011Bk jejich f\u00FAz\u00ED s permisivn\u00EDmi ku\u0159ec\u00EDmi fibroblasty. To otev\u0159elo cestu k porozum\u011Bn\u00ED nepermisivity v\u016F\u010Di retrovirov\u00E9 infekci."@cs . . . . "[21EFE032EAAC]" . "1;32" . "Twists and turns in life and science. Foundation Series in Cancer Research"@en . . . "400928" . "RIV/68378050:_____/08:00097944" . "Twists and turns in life and science. Foundation Series in Cancer Research" . . . . "This chapter provides a personal insight into the scientific and social atmosphere in former Czechoslovakia. It covers the period of the rise of Ha\u0161ek\u2019s immunologic school and application of immunologic tolerance to Rous sarcoma virus (RSV) heterotransmission. These approaches permitted establishment of a new model of mammalian cells transformed by RSV (virogenic XC cells), where the noninfectious viral genome was kept indefinitely as new genetic information (provirus). RSV was rescued from nonpermissive mammalian cells by fusion (complementation) with permissive chicken fibroblasts; this opened the way to understanding virus nonpermissiveness."@en . "99" . "Z(AV0Z50520514), Z(AV0Z5052915)" . "This chapter provides a personal insight into the scientific and social atmosphere in former Czechoslovakia. It covers the period of the rise of Ha\u0161ek\u2019s immunologic school and application of immunologic tolerance to Rous sarcoma virus (RSV) heterotransmission. These approaches permitted establishment of a new model of mammalian cells transformed by RSV (virogenic XC cells), where the noninfectious viral genome was kept indefinitely as new genetic information (provirus). RSV was rescued from nonpermissive mammalian cells by fusion (complementation) with permissive chicken fibroblasts; this opened the way to understanding virus nonpermissiveness." . . "RIV/68378050:_____/08:00097944!RIV08-AV0-68378050" . . "Klikat\u00E9 cesty \u017Eivota a v\u011Bdy. Zakladatelsk\u00E1 s\u00E9rie v\u00FDzkumu rakoviny"@cs . . "1" . . "Svoboda, Jan" . "Twists and turns in life and science. Foundation Series in Cancer Research"@en . "Twists and turns in life and science. Foundation Series in Cancer Research" . "Klikat\u00E9 cesty \u017Eivota a v\u011Bdy. Zakladatelsk\u00E1 s\u00E9rie v\u00FDzkumu rakoviny"@cs . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "cancer; oncogene; src"@en . "32"^^ . . "0065-230X" . "1"^^ . . "Advances in Cancer Research" . .