"P(IBS5052312), Z(AV0Z50520514)" . "Human allogeneic keratinocytes cultured on acellular xenodermis: the use in healing of burns and other skin defects"@en . . "\u0160tolbov\u00E1, V." . "acellular xenodermis; human keratinocytes; wound grafting"@en . . . . "9"^^ . "Bro\u017E, L." . . . "Klein, L." . "Human allogeneic keratinocytes cultured on acellular xenodermis: the use in healing of burns and other skin defects"@en . "Matou\u0161kov\u00E1, Eva" . "The tissue engineered skin should be composed of both dermal and epidermal layers. We combined cultured human allogeneic keratinocytes with acellular xenodermis prepared from pig xenografts. The composite skin can be cultured in undifferentiated or differentiated phenotype. The differentiated phenotype (D-RHPS) was grown at the air-liquid interface and formed 5-20 cell layers similar to the normal epidermis, including the granular and horny layers. Undifferentiated RHPS has skin-like consistency and has been successfully used for treatment of burns and skin defects using \u201Cupside-down\u201D application. Simple acellular xenodermis without keratinocytes can also be used as temporary cover for donor sites, leg ulcers and other skin defects."@en . "4" . "Lidsk\u00E9 alogenn\u00ED keratinocyty kultivovan\u00E9 na bezbun\u011B\u010Dn\u00E9 xenodermis: vyu\u017Eit\u00ED pro l\u00E9\u010Dbu pop\u00E1lenin a jin\u00FDch ko\u017En\u00EDch defekt\u016F"@cs . "2"^^ . "The tissue engineered skin should be composed of both dermal and epidermal layers. We combined cultured human allogeneic keratinocytes with acellular xenodermis prepared from pig xenografts. The composite skin can be cultured in undifferentiated or differentiated phenotype. The differentiated phenotype (D-RHPS) was grown at the air-liquid interface and formed 5-20 cell layers similar to the normal epidermis, including the granular and horny layers. Undifferentiated RHPS has skin-like consistency and has been successfully used for treatment of burns and skin defects using \u201Cupside-down\u201D application. Simple acellular xenodermis without keratinocytes can also be used as temporary cover for donor sites, leg ulcers and other skin defects." . . "RIV/68378050:_____/06:00044213" . "63;71" . . "RIV/68378050:_____/06:00044213!RIV07-AV0-68378050" . "16" . . . "Bio-Medical Materials and Engineering" . "Konigov\u00E1, R." . "NL - Nizozemsko" . "478390" . "Lidsk\u00E9 alogenn\u00ED keratinocyty kultivovan\u00E9 na bezbun\u011B\u010Dn\u00E9 xenodermis: vyu\u017Eit\u00ED pro l\u00E9\u010Dbu pop\u00E1lenin a jin\u00FDch ko\u017En\u00EDch defekt\u016F"@cs . . . . "[9ADEFB6350F8]" . "Um\u011Bl\u00E1 n\u00E1hrada k\u016F\u017Ee by m\u011Bla obsahovat derm\u00E1ln\u00ED i epiderm\u00E1ln\u00ED vrstvu. Kombinac\u00ED kultivovan\u00FDch lidsk\u00FDch keratinocyt\u016F a bezbun\u011B\u010Dn\u00E9 prase\u010D\u00ED dermis jsme vytvo\u0159ili um\u011Blou k\u016F\u017Ei, kterou je mo\u017Eno pou\u017E\u00EDt pro hojen\u00ED pop\u00E1lenin a jin\u00FDch ko\u017En\u00EDch defekt\u016F. Rekombinovan\u00E1 k\u016F\u017Ee kultivovan\u00E1 na rozhran\u00ED medium/vzduch byla tvo\u0159ena a\u017E dvaceti vrstvami diferencovan\u00FDch epiderm\u00E1ln\u00EDch bun\u011Bk. Nediferencovan\u00E1 forma k\u016F\u017Ee obsahovala 1-2 vrstvy epiderm\u00E1ln\u00EDch bun\u011Bk na xenodermis a dala se pou\u017E\u00EDt jako do\u010Dasn\u00FD kryt ran (aplikace bu\u0148kami do r\u00E1ny). Tak\u00E9 samotn\u00E1 bezbun\u011B\u010Dn\u00E1 xenodermis, kter\u00E1 m\u016F\u017Ee b\u00FDt skladov\u00E1na.steriln\u011B v such\u00E9m stavu, m\u016F\u017Ee b\u00FDt vyu\u017Eita pro hojen\u00ED odb\u011Brov\u00FDch ploch, b\u00E9rcov\u00FDch v\u0159ed\u016F, rozs\u00E1hl\u00FDch od\u0159enin apod."@cs . "0959-2989" . "Vesel\u00FD, Pavel" . "Human allogeneic keratinocytes cultured on acellular xenodermis: the use in healing of burns and other skin defects" . . . . . . "Human allogeneic keratinocytes cultured on acellular xenodermis: the use in healing of burns and other skin defects" . "6"^^ .