"Kubera, M." . "2"^^ . . "Effect of lipopolysaccharide and antidepressant drugs on glucocorticoid receptor-mediated gene transcription" . . "540;544" . . "Basta-Kaim, A." . "Zaj\u00EDcov\u00E1, Alena" . . . . "Budziszewska, B." . . "1734-1140" . "Jaworska, L." . "Leskiewicz, M." . . "RIV/68378050:_____/05:00025555" . "Otczyk, M." . . "Tetich, M." . "It has been hypothesized that pro-inflammatory response and hyperactivity of HPA axis are involved in the pathogenesis of depression. Previously we found that antidepressants inhibited glucocoticoid receptor (GR) function under the in vitro conditions. We investigated the effect of lipopolysaccharide (LPS) on imipramine- or fluoxetine-induced inhibition of GR-mediated gene transcription in fibroblast cells. The data suggested that pro-inflammatory agents facilitate antidepressant-induced inhibition of glucocorticoid receptor function."@en . "10"^^ . "5"^^ . "Effect of lipopolysaccharide and antidepressant drugs on glucocorticoid receptor-mediated gene transcription"@en . "Vliv lipopolysacharidu a antidepresiv na genovou transkripci zprost\u0159edkovanou glukokortikoidov\u00FDm receptorem"@cs . "Hol\u00E1\u0148, Vladim\u00EDr" . "Effect of lipopolysaccharide and antidepressant drugs on glucocorticoid receptor-mediated gene transcription"@en . "PL - Polsk\u00E1 republika" . "glucocorticoid receptor; antidepressant drugs; interleukin-6"@en . "57" . "Pharmacological Reports" . "Z(AV0Z5052915)" . "4" . "P\u0159edpokl\u00E1d\u00E1 se, \u017Ee proz\u00E1n\u011Btliv\u00E1 odpov\u011B\u010F a hyperaktivita HPA osy je zahrnuta v patogenesi deprese. Ji\u017E d\u0159\u00EDve jsme zjistili, \u017Ee antidepresiva inhibuj\u00ED v in vitro podm\u00EDnk\u00E1ch funkci glukokortikoidn\u00EDho receptoru (GR). Zkoumali jsme vliv LPS na imipramin- nebo fluoxetinem indukovanou inhibici GR ovlivn\u011Bn\u00E9 genov\u00E9 transkripce ve fibroblastech. V\u00FDsledky nazna\u010Duj\u00ED, \u017Ee proz\u00E1n\u011Btliv\u00E1 agens usnad\u0148uj\u00ED antidepresivy indukovanou inhibici funkce GR."@cs . "It has been hypothesized that pro-inflammatory response and hyperactivity of HPA axis are involved in the pathogenesis of depression. Previously we found that antidepressants inhibited glucocoticoid receptor (GR) function under the in vitro conditions. We investigated the effect of lipopolysaccharide (LPS) on imipramine- or fluoxetine-induced inhibition of GR-mediated gene transcription in fibroblast cells. The data suggested that pro-inflammatory agents facilitate antidepressant-induced inhibition of glucocorticoid receptor function." . "Effect of lipopolysaccharide and antidepressant drugs on glucocorticoid receptor-mediated gene transcription" . "519348" . . . "Vliv lipopolysacharidu a antidepresiv na genovou transkripci zprost\u0159edkovanou glukokortikoidov\u00FDm receptorem"@cs . . . . "RIV/68378050:_____/05:00025555!RIV06-AV0-68378050" . . . "Laso\u0144, W." . "[D8979205554A]" .