"2"^^ . . . "Trtkov\u00E1, Kate\u0159ina" . "2"^^ . "8-9" . "8"^^ . . "1071-2690" . . "RIV/68378050:_____/04:00000219" . "V dom\u00E9n\u00E1ch pro vazbu na DNA a pro oligomerizaci genu TP53 byly detegov\u00E1ny \u010Detn\u00E9 delece v pozdn\u00EDch i \u010Dasn\u00FDch in vitro pas\u00E1\u017E\u00EDch ku\u0159ec\u00ED n\u00E1dorov\u00E9 bun\u011B\u010Dn\u00E9 linie PR9692. Tato n\u00E1dorov\u00E1 bun\u011B\u010Dn\u00E1 linie vykazuje imortalizovan\u00FD fenotyp a z\u00EDskala schopnost metastazovat, kter\u00E1 je v\u00FDjime\u010Dn\u00E1 v r\u00E1mci na\u0161eho modelu n\u00E1dor\u016F vyvolan\u00FDch v-src u kongenn\u00EDch ku\u0159at."@cs . "Delece ve vazebn\u00E9 dom\u00E9n\u011B pro DNA genu TP53 u ku\u0159ec\u00EDch bun\u011Bk transformovan\u00FDch v-src"@cs . "avian; sarcoma; immortalization"@en . "Delece ve vazebn\u00E9 dom\u00E9n\u011B pro DNA genu TP53 u ku\u0159ec\u00EDch bun\u011Bk transformovan\u00FDch v-src"@cs . . . . . "40" . . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . . . . "In Vitro - Cellular and Developmental Biology. Animal Section" . "Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells" . . . "Plach\u00FD, Ji\u0159\u00ED" . "We have detected frequent deletions of variable length in both DNA-binding and oligomerization domains of the TP53 in the late as well as early in vitro passages of the chicken tumor cell line PR9692. This tumor cell line shows an immortal phenotype and acquires a metastatic potential that is unique in our experimental model of v-src-induced tumors in congenic chicken." . . "559667" . "Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells"@en . "RIV/68378050:_____/04:00000219!RIV/2005/AV0/A23005/N" . "285;292" . . "Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells"@en . "[A7EB2D2028A2]" . "We have detected frequent deletions of variable length in both DNA-binding and oligomerization domains of the TP53 in the late as well as early in vitro passages of the chicken tumor cell line PR9692. This tumor cell line shows an immortal phenotype and acquires a metastatic potential that is unique in our experimental model of v-src-induced tumors in congenic chicken."@en . "Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells" . "P(GA204/02/0407), Z(AV0Z5052915)" .