. . "Genes and immunity" . "The strain BALB/cHeA (BALB/c) is a high producer, and STS/A (STS) a low producer of IgE after Leishmania major infection. We analyzed this strain difference using 20 recombinant congenic (RC) BALB/c-c-STS/Dem (CcS/Dem) strains that carry different random subsets of 12.5% of genes of the strain STS on the BALB/c background. Strains CcS-16 and -20 exhibit a high and a low IgE level, respectively. In their F, hybrids with BALBIc we mapped nine Leishmania major response (Lmr) loci. Two of them we previously found to influence IgE level in CcS-5. IgE production in CcS-16 is controlled by loci on chromosomes 2, 10, 16 and 18 and in CcS-20 by loci on chromosomes 1, 3, 4, 5 and 8. The STS alleles of loci on chromosomes 1, 4, 5, 8 and 10 were associated with a low, whereas the STS alleles on chromosomes 16 and 18 with a high IgE production. The loci on chromosomes 2 and 3 have no apparent individual effect, but interact with the loci on chromosomes 10 and 1, respectively. The loci on chromosomes 10 and 18 were"@en . "1466-4879" . "5"^^ . "IgE; quantitative trait; Leishmania major,"@en . . . . "Vladimirov, Vladimir" . "P(GA310/00/0760), P(NM28), P(OK 394), Z(AV0Z5052915)" . "Vladimirov, Vladimir" . "10"^^ . . "9"^^ . . "Vojt\u00ED\u0161kov\u00E1, Jarmila" . "[7CDE30B6C276]" . "Svobodov\u00E1, M." . "Separation and mapping of multiple genes that control IgE level in Leishmania major infected mice." . . "0"^^ . . "0"^^ . . "Separation and mapping of multiple genes that control IgE level in Leishmania major infected mice."@en . "Volf, P." . . "663318" . . . "Separation and mapping of multiple genes that control IgE level in Leishmania major infected mice."@en . "Demant, P." . . "Pil\u010D\u00EDk, Tom\u00E1\u0161" . "Engov\u00E1, J." . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "Separation and mapping of multiple genes that control IgE level in Leishmania major infected mice." . . . "RIV/68378050:_____/02:23033175!RIV/2004/AV0/A23004/N" . "B\u00E1dalov\u00E1, J." . . "3" . "2002" . "The strain BALB/cHeA (BALB/c) is a high producer, and STS/A (STS) a low producer of IgE after Leishmania major infection. We analyzed this strain difference using 20 recombinant congenic (RC) BALB/c-c-STS/Dem (CcS/Dem) strains that carry different random subsets of 12.5% of genes of the strain STS on the BALB/c background. Strains CcS-16 and -20 exhibit a high and a low IgE level, respectively. In their F, hybrids with BALBIc we mapped nine Leishmania major response (Lmr) loci. Two of them we previously found to influence IgE level in CcS-5. IgE production in CcS-16 is controlled by loci on chromosomes 2, 10, 16 and 18 and in CcS-20 by loci on chromosomes 1, 3, 4, 5 and 8. The STS alleles of loci on chromosomes 1, 4, 5, 8 and 10 were associated with a low, whereas the STS alleles on chromosomes 16 and 18 with a high IgE production. The loci on chromosomes 2 and 3 have no apparent individual effect, but interact with the loci on chromosomes 10 and 1, respectively. The loci on chromosomes 10 and 18 were" . "RIV/68378050:_____/02:23033175" . "Lipoldov\u00E1, Marie" . . . . "187;195" . "Havelkov\u00E1, Helena" . . .