. "Suppl.57" . "RIV/68378050:_____/02:00105315!RIV/2005/AV0/A23005/N" . "Genetic analysis of IgE expression" . . . "Genetick\u00E1 anal\u00FDza exprese IgE"@cs . . "1"^^ . "Anal\u00FDza funkce gen\u016F \u0159\u00EDd\u00EDc\u00EDch expresi cytokin\u016F ve zdrav\u00ED a v nemoci. Srovn\u00E1vali jsme produkci IL-4 a IL-10 v neinfek\u010Dn\u00EDch my\u0161\u00EDch a v my\u0161\u00EDch infikovan\u00FDch Leishmania major a zjistili jsme, \u017Ee gen Cypr3 (cytokine production 3) ovliv\u0148uje expresi cytokin\u016F v infikovan\u00FDch i neinfikovan\u00FDch my\u0161\u00EDch, zat\u00EDmco vliv Cypr1 je omezen na n\u011Bkter\u00E9 stavy (neinfikovan\u00E9 my\u0161i). Cypr2 je um\u00EDst\u011Bn spole\u010Dn\u011B s lokusem Lmr8 (Leishmania major response 8) na chromozomu 1, kter\u00FD \u0159\u00EDd\u00ED produkci IgE po infekci L. major. Tyto v\u00FDsledky by mohly nazna\u010Dovat, \u017Ee existuje p\u0159\u00ED\u010Dinn\u00E1 vazba mezi t\u011Bmito dv\u011Bma lokusy nebo \u017Ee ob\u011B tyto funkce jsou \u0159\u00EDzeny stejn\u00FDm genem"@cs . "Genetic analysis of IgE expression" . "57" . "Genetic analysis of IgE expression"@en . "646932" . . . . . "Genetic analysis of IgE expression"@en . "140" . . . "RIV/68378050:_____/02:00105315" . "Havelkov\u00E1, Helena" . . "Bla\u017Ekov\u00E1, Hana" . "P(GP310/02/P141), Z(AV0Z5052915)" . . "5"^^ . "gene; QTL; cytokine"@en . . "[13390876BAE0]" . . . . . "Allergy" . "Analysis of function of genes that control the expression of cytokines in health and disease. We have compared production of IL-4 and IL-10 in uninfected mice and in mice infected by Leishmania major and we have found that gene Cypr3 (cytokine production 3) influences cytokine expression both in uninfected and infected mice, whereas the influence of Cypr1 is restricted to certain conditions (uninfected mice). Cypr2 colocalizes with locus Lmr8 (Leishmania major response 8) on chromosome 1 that controls IgE production after L. major infection. These results might indicate either causal link between these two loci or that both functions are controlled by the same gene"@en . "DK - D\u00E1nsk\u00E9 kr\u00E1lovstv\u00ED" . "Analysis of function of genes that control the expression of cytokines in health and disease. We have compared production of IL-4 and IL-10 in uninfected mice and in mice infected by Leishmania major and we have found that gene Cypr3 (cytokine production 3) influences cytokine expression both in uninfected and infected mice, whereas the influence of Cypr1 is restricted to certain conditions (uninfected mice). Cypr2 colocalizes with locus Lmr8 (Leishmania major response 8) on chromosome 1 that controls IgE production after L. major infection. These results might indicate either causal link between these two loci or that both functions are controlled by the same gene" . "Kosa\u0159ov\u00E1, Marcela" . . "Lipoldov\u00E1, Marie" . "4"^^ . "Kr\u00E1l, V." . . . "0105-4538" . "Genetick\u00E1 anal\u00FDza exprese IgE"@cs .