. "We investigated associations between the levels of 8-oxo-7,8-dihydro-2\u2019-deoxyguanosine (8-oxodG), a marker of oxidative DNA damage, in placental DNA, exposure to air pollutants during pregnancy, genetic polymorphisms in 94 selected genes and pregnancy outcomes (intrauterine growth restriction, IUGR, low birth weight, LBW). Multivariate-adjusted logistic regression revealed that above-median 8-oxodG levels are the only factor significantly associated with the risk of IUGR (OR; 95% CI: 1.56; 1.07-2.37; p=0.022). Above-median levels of 8-oxodG were associated with an increased risk of LBW (OR; 95% CI: 1.88; 1.15- 3.06; p=0.011). Other variables associated with LBW included the newborn\u2019s gender and gestational age, maternal smoking and haplotypes in the promoter region of the gene encoding mannose-binding lectin 2."@en . "\u0160p\u00E1tov\u00E1, Milada" . "119" . . "200983" . "7"^^ . . . . . "We investigated associations between the levels of 8-oxo-7,8-dihydro-2\u2019-deoxyguanosine (8-oxodG), a marker of oxidative DNA damage, in placental DNA, exposure to air pollutants during pregnancy, genetic polymorphisms in 94 selected genes and pregnancy outcomes (intrauterine growth restriction, IUGR, low birth weight, LBW). Multivariate-adjusted logistic regression revealed that above-median 8-oxodG levels are the only factor significantly associated with the risk of IUGR (OR; 95% CI: 1.56; 1.07-2.37; p=0.022). Above-median levels of 8-oxodG were associated with an increased risk of LBW (OR; 95% CI: 1.88; 1.15- 3.06; p=0.011). Other variables associated with LBW included the newborn\u2019s gender and gestational age, maternal smoking and haplotypes in the promoter region of the gene encoding mannose-binding lectin 2." . . "7"^^ . . "0091-6765" . . "P(SP/1B3/50/07), Z(AV0Z50390512)" . "Chv\u00E1talov\u00E1, Irena" . "[A72E4077DB20]" . . "Dost\u00E1l, Miroslav" . "Environmental Health Perspectives" . . "7"^^ . . "RIV/68378041:_____/11:00356231!RIV11-MZP-68378041" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "Genetic, Biochemical and Environmental Factors Associated with Pregnancy Outcomes in Newborns from the Czech Republic"@en . "2" . . . "000286803400031" . . "Genetic, Biochemical and Environmental Factors Associated with Pregnancy Outcomes in Newborns from the Czech Republic" . . . . . "RIV/68378041:_____/11:00356231" . "Genetic, Biochemical and Environmental Factors Associated with Pregnancy Outcomes in Newborns from the Czech Republic"@en . "air pollution; biomarkers; genetic polymorphisms"@en . "Tabashidze, Nana" . . . "R\u00F6ssner ml., Pavel" . "\u0160r\u00E1m, Radim" . . "Genetic, Biochemical and Environmental Factors Associated with Pregnancy Outcomes in Newborns from the Czech Republic" . . . "Nov\u00E1kov\u00E1, Zuzana" .