. "Repeated administration of higher doses (25 mg/kg) of tenofovir to rats decreases the relative proportion of active liver microsomal cytochrome P450. These enzymes are denaturated to the inactive form of cytochrome (CYPP420)."@en . "[7F415145A830]" . . "371794" . "Nekvindov\u00E1, J." . "5" . "Tenofovir; PMPA; Cytochrome P450"@en . "Z\u00EDdek, Zden\u011Bk" . "CZ - \u010Cesk\u00E1 republika" . "Repeated administration of higher doses (25 mg/kg) of tenofovir to rats decreases the relative proportion of active liver microsomal cytochrome P450. These enzymes are denaturated to the inactive form of cytochrome (CYPP420)." . . . "In vivo studie vlivu acyklick\u00E9ho nukleosidfosfon\u00E1tu (R)-9-[2-(phosphonomethoxy)propyl]adeninu (PMPA, tenofovir) a jeho prodrug tenofoviru disoproxil fumar\u00E1tu na potkan\u00ED mikrosom\u00E1ln\u00ED cytochrom P450"@cs . "0862-8408" . "260893500013" . "9"^^ . "Kmon\u00ED\u010Dkov\u00E1, Eva" . . "Hol\u00FD, Anton\u00EDn" . . "In vivo study of the effect of antiviral acyclic nucleotide phosphonate (R)-9-[2 -(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and its prodrug tenofovir disoproxil fumarate on rat microsomal cytochrome P450"@en . . . . . . "In vivo studie vlivu acyklick\u00E9ho nukleosidfosfon\u00E1tu (R)-9-[2-(phosphonomethoxy)propyl]adeninu (PMPA, tenofovir) a jeho prodrug tenofoviru disoproxil fumar\u00E1tu na potkan\u00ED mikrosom\u00E1ln\u00ED cytochrom P450"@cs . "In vivo study of the effect of antiviral acyclic nucleotide phosphonate (R)-9-[2 -(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and its prodrug tenofovir disoproxil fumarate on rat microsomal cytochrome P450" . "RIV/68378041:_____/08:00315836!RIV09-AV0-68378041" . . "Anzenbacher, P." . "4"^^ . "57" . . . . . "7"^^ . . "In vivo study of the effect of antiviral acyclic nucleotide phosphonate (R)-9-[2 -(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and its prodrug tenofovir disoproxil fumarate on rat microsomal cytochrome P450"@en . "Physiological Research" . . . . . "Buchar, Ev\u017Een" . "Veinlichov\u00E1, A." . "RIV/68378041:_____/08:00315836" . "Anzenbacherov\u00E1, E." . "In vivo study of the effect of antiviral acyclic nucleotide phosphonate (R)-9-[2 -(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and its prodrug tenofovir disoproxil fumarate on rat microsomal cytochrome P450" . "P(1M0508), Z(AV0Z40550506), Z(AV0Z50390512), Z(MSM6198959216)" . "Potm\u011B\u0161il, Petr" . . "Opakovan\u00E9 pod\u00E1v\u00E1n\u00ED tenofoviru potkan\u016Fm v d\u00E1vce 25 mg/kg vedlo ke sn\u00ED\u017Een\u00ED relativn\u00EDho zastoupen\u00ED aktivn\u00ED formy cytochromu P450 v jatern\u00EDch mikrosomech. Tyto enzymy byly \u010D\u00E1ste\u010Dn\u011B denaturov\u00E1ny na neaktivn\u00ED formu, tj. cytochrom P420."@cs .