"PL - Polsk\u00E1 republika" . "RIV/68081707:_____/07:00087650!RIV08-AV0-68081707" . "\u00DAloha aktinov\u00FDch a mikrotubul\u00E1rn\u00EDch s\u00EDt\u00ED ve vnitrobun\u011B\u010Dn\u00E9m transportu plasmidov\u00E9 DNA"@cs . "[D0AF8729B36C]" . "448164" . "\u00DAloha aktinov\u00FDch a mikrotubul\u00E1rn\u00EDch s\u00EDt\u00ED ve vnitrobun\u011B\u010Dn\u00E9m transportu plasmidov\u00E9 DNA"@cs . . "This work is focused on the function of the microtubule and actin networks in plasmid DNA transport during liposomal transfection. We observed strong binding of plasmid DNA-lipid complexes to both networks. Disruption of either of these networks led to the cessation of plasmid transport to the nucleus and accumulation of plasmid DNA in large aggregates at the cell periphery." . "The role of actin and microtubule networks in plasmid DNA intracellular trafficking"@en . "The role of actin and microtubule networks in plasmid DNA intracellular trafficking" . . . . . . "Ond\u0159ej, Vladan" . "3" . . . "7"^^ . . . . . "0001-527X" . . "54" . "Falk, Martin" . . "657;663" . . . "The role of actin and microtubule networks in plasmid DNA intracellular trafficking" . . "The role of actin and microtubule networks in plasmid DNA intracellular trafficking"@en . . "Kozubek, Stanislav" . "Acta Biochimica Polonica" . . "Luk\u00E1\u0161ov\u00E1, Emilie" . . "plasmid DNA; actin filaments; microtubules"@en . "P(1QS500040508), P(GA202/02/0804), P(GA202/04/0907), P(LC535), Z(AV0Z50040507), Z(AV0Z50040702)" . . "Tato pr\u00E1ce je zam\u011B\u0159ena na pozn\u00E1n\u00ED funkce acetinov\u00E9ho a mikrotubul\u00E1rn\u00EDho cytoskeletu v transportu plasmidov\u00E9 DNA b\u011Bhem lipozom\u00E1ln\u00ED transfekce. Pozorovali jsme silnou vazbu komplex\u016F plasmidov\u00E9 DNA a lipid\u016F k ob\u011Bma cytoskelet\u00E1rn\u00EDm s\u00EDt\u00EDm. Naru\u0161en\u00ED t\u011Bchto s\u00EDt\u00ED vedlo k zastaven\u00ED transpjortu plasmid\u016F do bun\u011B\u010Dn\u00E9ho j\u00E1dra a k akumulaci plasmidov\u00E9 DNA do velk\u00FDch agreg\u00E1t\u016F lokalizovan\u00FDch na periferii bun\u011Bk."@cs . "This work is focused on the function of the microtubule and actin networks in plasmid DNA transport during liposomal transfection. We observed strong binding of plasmid DNA-lipid complexes to both networks. Disruption of either of these networks led to the cessation of plasmid transport to the nucleus and accumulation of plasmid DNA in large aggregates at the cell periphery."@en . . "4"^^ . "RIV/68081707:_____/07:00087650" . . "4"^^ . .