"Electrochemical Sensing of Chromium \u2013 Induced DNA Damane: DNA Strand Breakage by Intermediates of Chromium (VI) Electrochemical Reduction"@en . . . . "Chromium electrochemical reduction; DNA damage; DNA-modified electrode; Reactive oxygen species; Guanine modification; Magnetic separation"@en . . . "Elektrochemick\u00E1 detekce po\u0161kozen\u00ED DNA indukovan\u00E9ho slou\u010Deninami chr\u00F3mu: \u0161t\u011Bpen\u00ED \u0159et\u011Bzc\u016F DNA meziprodukty elektrochemick\u00E9 redukce Cr(VI)" . . . "2093-2102" . "19" . . "V t\u00E9to pr\u00E1ci je pops\u00E1n vliv elektrochemick\u00E9 redukce Cr(VI) na po\u0161kozen\u00ED DNA, kter\u00E1 byla adsorbov\u00E1na na povrch rtu\u0165ov\u00E9 elektrody. Tak\u00E9 jsou v pr\u00E1ci zve\u0159ejn\u011Bny v\u00FDsledky m\u011B\u0159en\u00ED \u00FA\u010Dinku Cr(VI) a reduk\u010Dn\u00EDho \u010Dinidla ( kyselina askorbov\u00E9) na po\u0161kozen\u00ED DNA. K detekci modifikace guaninov\u00FDch zbytk\u016F byla pou\u017Eita dvoupovrchov\u00E1-technika kde krom\u011B rtu\u0165ov\u00E9 elektrody byla pou\u017Eita i elektroda uhl\u00EDkov\u00E1. Na\u0161e v\u00FDsledky ukazuj\u00ED na mo\u017Enost vyu\u017Eit\u00ED elektrochemick\u00E9 redukce Cr(VI) p\u0159i studiu po\u0161kozen\u00ED DNA na povrchu elektrody je efektivn\u011Bj\u0161\u00ED ne\u017E reakce prob\u00EDhaj\u00EDc\u00ED za standardn\u00EDch podm\u00EDnek v roztoku." . "[4765A3DE49AF]" . . . "Vacek, Jan" . . . . "P(1H-PK/42), P(GA203/07/1195), P(LC06035), Z(AV0Z50040507), Z(AV0Z50040702)" . "RIV/68081707:_____/07:#0000007!RIV08-MPO-68081707" . "Elektrochemick\u00E1 detekce po\u0161kozen\u00ED DNA indukovan\u00E9ho slou\u010Deninami chr\u00F3mu: \u0161t\u011Bpen\u00ED \u0159et\u011Bzc\u016F DNA meziprodukty elektrochemick\u00E9 redukce Cr(VI)" . "Electrochemical Sensing of Chromium \u2013 Induced DNA Damane: DNA Strand Breakage by Intermediates of Chromium (VI) Electrochemical Reduction"@en . . "V t\u00E9to pr\u00E1ci je pops\u00E1n vliv elektrochemick\u00E9 redukce Cr(VI) na po\u0161kozen\u00ED DNA, kter\u00E1 byla adsorbov\u00E1na na povrch rtu\u0165ov\u00E9 elektrody. Tak\u00E9 jsou v pr\u00E1ci zve\u0159ejn\u011Bny v\u00FDsledky m\u011B\u0159en\u00ED \u00FA\u010Dinku Cr(VI) a reduk\u010Dn\u00EDho \u010Dinidla ( kyselina askorbov\u00E9) na po\u0161kozen\u00ED DNA. K detekci modifikace guaninov\u00FDch zbytk\u016F byla pou\u017Eita dvoupovrchov\u00E1-technika kde krom\u011B rtu\u0165ov\u00E9 elektrody byla pou\u017Eita i elektroda uhl\u00EDkov\u00E1. Na\u0161e v\u00FDsledky ukazuj\u00ED na mo\u017Enost vyu\u017Eit\u00ED elektrochemick\u00E9 redukce Cr(VI) p\u0159i studiu po\u0161kozen\u00ED DNA na povrchu elektrody je efektivn\u011Bj\u0161\u00ED ne\u017E reakce prob\u00EDhaj\u00EDc\u00ED za standardn\u00EDch podm\u00EDnek v roztoku."@cs . . . . "5"^^ . . "RIV/68081707:_____/07:#0000007" . "DE - Spolkov\u00E1 republika N\u011Bmecko" . . . "19-20" . "Fojta, Miroslav" . . . "5"^^ . "1040-0397" . . "Elektrochemick\u00E1 detekce po\u0161kozen\u00ED DNA indukovan\u00E9ho slou\u010Deninami chr\u00F3mu: \u0161t\u011Bpen\u00ED \u0159et\u011Bzc\u016F DNA meziprodukty elektrochemick\u00E9 redukce Cr(VI)"@cs . "10"^^ . "Cahov\u00E1, Kate\u0159ina" . "Electroanalysis" . . "419817" . "Mozga, Tom\u00E1\u0161" . . "DNA damage by Cr V and/or Cr IV intermediates of Cr VI electrochemical reduction was detected us\u00E1ny a supercoiled DNA \u2013modified merkury electrodes. Damage to DNA in solution containing Cr IV and chemical reductant ( ascorbic acids) was observed too. To eliminace interference of excess Cr VI in measurements of guanine electrochemical signals, a magnetoseparation double surface electrochemical technique was introduced. Our results suggest a mode efficient DNA damage at the electrode sulface due to continuous production of the reactive chromium species, compared to DNA exposure to chromium in solution."@en . . . "Elektrochemick\u00E1 detekce po\u0161kozen\u00ED DNA indukovan\u00E9ho slou\u010Deninami chr\u00F3mu: \u0161t\u011Bpen\u00ED \u0159et\u011Bzc\u016F DNA meziprodukty elektrochemick\u00E9 redukce Cr(VI)"@cs . "Pivo\u0148kov\u00E1, Hana" .