"Mercury film electrodes (MFE) have recently been used in nucleic acid electrochemical analysis as alternatives to the classical mercury drop ones. DNA modified with osmium tetroxide, 2,2' -bipyridine (Os,bipy) can be detected with a high sensitivity at mercury electrodes via measurements of a catalytic osmiurn signal. In this paper we show that mercury film on a glassy carbon electrode can be used in voltammetric analysis of Os,bipy-modified DNA. Application of the MFE as a detection electrode in double-surface electrochemical DNA hybridization assay involving osmium labeling of target DNA is demonstrated."@en . . . "Fojta, Miroslav" . "Bioelectrochemistry" . "1567-5394" . . . "osmium; DNA hybridization; mercury film electrode"@en . . . . "4"^^ . "1-2" . . "245;248" . . "CH - \u0160v\u00FDcarsk\u00E1 konfederace" . "Pivo\u0148kov\u00E1, Hana" . "593287" . "4"^^ . . "RIV/68081707:_____/04:00104623!RIV/2005/AV0/A17005/N" . . "Mercury film electrodes (MFE) have recently been used in nucleic acid electrochemical analysis as alternatives to the classical mercury drop ones. DNA modified with osmium tetroxide, 2,2' -bipyridine (Os,bipy) can be detected with a high sensitivity at mercury electrodes via measurements of a catalytic osmiurn signal. In this paper we show that mercury film on a glassy carbon electrode can be used in voltammetric analysis of Os,bipy-modified DNA. Application of the MFE as a detection electrode in double-surface electrochemical DNA hybridization assay involving osmium labeling of target DNA is demonstrated." . "Voltammetry of osmium-modified DNA at a mercury film electrode application in detecting DNA hybridization" . . . "4"^^ . . "Havran, Lud\u011Bk" . "Koste\u010Dka, Pavel" . "RIV/68081707:_____/04:00104623" . "[A423724843D2]" . . . "Voltammetry of osmium-modified DNA at a mercury film electrode application in detecting DNA hybridization"@en . . "Rtu\u0165ov\u00E9 filmov\u00E9 elektrody jsou v sou\u010Dasn\u00E9 dob\u011B vyu\u017E\u00EDv\u00E1ny v elektrochemick\u00E9 anal\u00FDze nukleov\u00FDch kyselin jako alternativy ke klasick\u00E9 rtu\u0165ov\u00E9 kapkov\u00E9 elektrod\u011B. DNA modifikovan\u00E1 komplexem oxidu osmi\u010Del\u00E9ho s 2,2\u00B4-bipyridinem (Os,bipy) m\u016F\u017Ee b\u00FDt citliv\u011B stanovena na rtu\u0165ov\u00FDch elektrod\u00E1ch s vyu\u017Eit\u00EDm katalytick\u00E9ho sign\u00E1lu osmia. V t\u00E9to pr\u00E1ci jsme uk\u00E1zali, \u017Ee rtu\u0165ov\u00FD film na elektrod\u011B ze skeln\u00E9ho uhl\u00EDku je vhodn\u00FD pro voltametrickou anal\u00FDzu DNA modifikovan\u00E9 Os,bipy a m\u016F\u017Ee slou\u017Eit jako detek\u010Dn\u00ED elektroda v dvoupovrchov\u00E9 elektrochemick\u00E9 anal\u00FDze hybridizace DNA."@cs . "Voltametrie DNA modifikovan\u00E9 osmiem na rtu\u0165ov\u00E9 filmov\u00E9 elektrod\u011B. Vyu\u017Eit\u00ED p\u0159i detekci hybridizace DNA"@cs . "Voltametrie DNA modifikovan\u00E9 osmiem na rtu\u0165ov\u00E9 filmov\u00E9 elektrod\u011B. Vyu\u017Eit\u00ED p\u0159i detekci hybridizace DNA"@cs . . . . "Voltammetry of osmium-modified DNA at a mercury film electrode application in detecting DNA hybridization" . "P(IAA4004108), P(KJB4004302), Z(AV0Z5004920)" . "63" . "Voltammetry of osmium-modified DNA at a mercury film electrode application in detecting DNA hybridization"@en . .