. "0"^^ . "Brabec, Viktor" . "Zehnulov\u00E1, Jana" . "Conformation, Recognition by High Mobility Group Domain Proteins, and Nucleotide Excision Repair of DNA Intrastrand Cross-links of Novel Antitumor Trinuclear Platinum Complex BBR3464."@en . . "RIV/68081707:_____/01:17013054!RIV/2003/AV0/A17003/N" . "3"^^ . . . . . . "Journal of Biological Chemistry" . . . . . "[92238F9501F0]" . "Conformation, Recognition by High Mobility Group Domain Proteins, and Nucleotide Excision Repair of DNA Intrastrand Cross-links of Novel Antitumor Trinuclear Platinum Complex BBR3464." . . . . "RIV/68081707:_____/01:17013054" . "25" . "676256" . "The novel antitumor platinum drug BBR3464 forms on DNA intrastrand adducts which change its local conformation in a way that they do not induce a stable curvature. These intrastrand adducts are not recognized by HMG domain proteins, but they are effectively removed from DNA by nucleotide excision repair. It has been concluded that the processing of these adducts in tumor cells may not be relevant to the antitumor effect of BBR3464"@en . "Farrell, N." . . "cisplatin-modified DNA; drug cis-diamminedichloroplatinum(II),"@en . "P(GA305/99/0695), P(IAA5004101), P(NL6058), Z(AV0Z5004920)" . "The novel antitumor platinum drug BBR3464 forms on DNA intrastrand adducts which change its local conformation in a way that they do not induce a stable curvature. These intrastrand adducts are not recognized by HMG domain proteins, but they are effectively removed from DNA by nucleotide excision repair. It has been concluded that the processing of these adducts in tumor cells may not be relevant to the antitumor effect of BBR3464" . . "22191;22199" . "0021-9258" . . . . "9"^^ . "Ka\u0161p\u00E1rkov\u00E1, Jana" . "Conformation, Recognition by High Mobility Group Domain Proteins, and Nucleotide Excision Repair of DNA Intrastrand Cross-links of Novel Antitumor Trinuclear Platinum Complex BBR3464."@en . "Conformation, Recognition by High Mobility Group Domain Proteins, and Nucleotide Excision Repair of DNA Intrastrand Cross-links of Novel Antitumor Trinuclear Platinum Complex BBR3464." . "276" . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "0"^^ . "4"^^ .