. "Slovinsk\u00E1, L." . "Motl\u00EDk, Jan" . "15"^^ . "Response of Ependymal Progenitors to Spinal Cord Injury or Enhanced Physical Activity in Adult Rat" . "6-7" . . "Nagyov\u00E1, M." . "0272-4340" . . . "29" . "Tomori, Z." . . "Response of Ependymal Progenitors to Spinal Cord Injury or Enhanced Physical Activity in Adult Rat"@en . "P(MEB0808108), Z(AV0Z50450515)" . "12"^^ . "\u010C\u00ED\u017Ekov\u00E1, D." . "Response of Ependymal Progenitors to Spinal Cord Injury or Enhanced Physical Activity in Adult Rat"@en . "Mechirov\u00E1, E." . . . . "Ependymal cells (EC) in the spinal cord central canal (CC) are believed to be responsible for the postnatal neurogenesis following pathological or stimulatory conditions. In this study, we have analyzed the proliferation of the CC ependymal progenitors in adult rats processed to compression SCI or enhanced physical activity. To label dividing cells, a single daily injection of Bromo-deoxyuridine (BrdU) was administered over a 14-day-survival period. Systematic quantification of BrdU-positive ependymal progenitors was performed by using stereological principles of systematic, random sampling, and optical Dissector software. The number of proliferating BrdUlabeled EC increased gradually with the time of survival after both paradigms, spinal cord injury, or increased physical activity. In the spinal cord injury group, we have found 4.9-fold (4 days), 7.1-fold (7 days), 4.9-fold (10 days), and 5.6-fold (14 days) increase of proliferating EC in the rostro-caudal regions, 4 mm away from the epicenter. In..."@en . "RIV/67985904:_____/09:00328392!RIV10-MSM-67985904" . . "Cellular and Molecular Neurobiology" . "2"^^ . . "Response of Ependymal Progenitors to Spinal Cord Injury or Enhanced Physical Activity in Adult Rat" . "RIV/67985904:_____/09:00328392" . . . "000268482300027" . . "Novotn\u00E1, I." . . "Ependymal cells (EC) in the spinal cord central canal (CC) are believed to be responsible for the postnatal neurogenesis following pathological or stimulatory conditions. In this study, we have analyzed the proliferation of the CC ependymal progenitors in adult rats processed to compression SCI or enhanced physical activity. To label dividing cells, a single daily injection of Bromo-deoxyuridine (BrdU) was administered over a 14-day-survival period. Systematic quantification of BrdU-positive ependymal progenitors was performed by using stereological principles of systematic, random sampling, and optical Dissector software. The number of proliferating BrdUlabeled EC increased gradually with the time of survival after both paradigms, spinal cord injury, or increased physical activity. In the spinal cord injury group, we have found 4.9-fold (4 days), 7.1-fold (7 days), 4.9-fold (10 days), and 5.6-fold (14 days) increase of proliferating EC in the rostro-caudal regions, 4 mm away from the epicenter. In..." . . "Rado\u0148\u00E1k, J." . . "\u010C\u00ED\u017Eek, M." . "Hlu\u010Dilov\u00E1, Jana" . "Vanick\u00FD, I." . . "Sulla, I." . "Spinal cord injury; Neural stem cells; BrdU"@en . "[3E56EAA9200E]" . "339172" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . .