"Embryogenesis of the heart muscle" . . . . . . "366036" . "Sedmera, David" . "RIV/67985904:_____/08:00316944" . "Myocardium is derived from precardiac mesoderm, and its formation is subject of positive and negative regulation by a number of genes. After formation of a tubular heart with a mode of contraction distinct from subsequent stages, initial increase in ventricular mass during the period of chamber formation is achieved by development of trabeculations, a hallmark of sponge-like hearts. Similar structures (pectinate muscles) develop later on in the atria. Trabecular compaction coincides with deployment of coronary circulation, and results in formation of ventricular chambers with significant, vascularized compact layers and clearly delineated lumen, which are capable of superior performance (pressure generation, ejection fraction) than the avascular, spongy ventricles. The contraction of the developing heart is orchestrated by its pacemaking and conduction system, which develops and changes parallel to heart morphogenesis. While the molecular determination of the sinoatrial node and atrioventricular wa..."@en . . "1"^^ . "Embryogenesis of the heart muscle" . "McQuinn, T. C." . . . "Heart Failure Clinics" . "11"^^ . "Embryogenesis of the heart muscle"@en . "2"^^ . "4" . "Myocardium is derived from precardiac mesoderm, and its formation is subject of positive and negative regulation by a number of genes. After formation of a tubular heart with a mode of contraction distinct from subsequent stages, initial increase in ventricular mass during the period of chamber formation is achieved by development of trabeculations, a hallmark of sponge-like hearts. Similar structures (pectinate muscles) develop later on in the atria. Trabecular compaction coincides with deployment of coronary circulation, and results in formation of ventricular chambers with significant, vascularized compact layers and clearly delineated lumen, which are capable of superior performance (pressure generation, ejection fraction) than the avascular, spongy ventricles. The contraction of the developing heart is orchestrated by its pacemaking and conduction system, which develops and changes parallel to heart morphogenesis. While the molecular determination of the sinoatrial node and atrioventricular wa..." . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "[3E3EF4DDC0F4]" . . "RIV/67985904:_____/08:00316944!RIV09-AV0-67985904" . "Embryogeneze srde\u010Dn\u00EDho svalu"@cs . . "Embryogenesis of the heart muscle"@en . . . "1551-7136" . "heart development; myocardium; microscopy"@en . "Embryogeneze srde\u010Dn\u00EDho svalu"@cs . . "P\u0159ehledn\u00FD \u010Dl\u00E1nek popisuj\u00EDc\u00ED v\u00FDvoj architektury myokardu za v\u00FDvoje a postup diferenciace p\u0159evodn\u00EDho syst\u00E9mu. C\u00EDlovou skupinou jsou d\u011Bt\u0161t\u00ED a dosp\u011Bl\u00ED kardiologov\u00E9."@cs . "-" . "Z(AV0Z50450515), Z(AV0Z5045916), Z(MSM0021620806)" . . . .