"canis familiaris; FSCN2 gene; PCR-RFLP"@en . "Journal of Applied Genetics" . "[C7E4F4B5ADD9]" . "Knoll, Ale\u0161" . . "Gen retin\u00E1ln\u00EDho fascinu 2 (FSCN2) \u2013 \u010D\u00E1ste\u010Dn\u00E1 strukturn\u00ED anal\u00FDza a detekce polymorfismu u ps\u016F posti\u017Een\u00FDch progresivn\u00ED retin\u00E1ln\u00ED atrofi\u00ED (PRA)"@cs . "RIV/67985904:_____/06:00045049!RIV07-AV0-67985904" . . . . "P(1QS500450578), Z(AV0Z50450515)" . "Gen retin\u00E1ln\u00EDho fascinu 2 (FSCN2) \u2013 \u010D\u00E1ste\u010Dn\u00E1 strukturn\u00ED anal\u00FDza a detekce polymorfismu u ps\u016F posti\u017Een\u00FDch progresivn\u00ED retin\u00E1ln\u00ED atrofi\u00ED (PRA)"@cs . . "The retinal fascin gene 2 (FSCN2) - partial structural analysis and polymorphisms detection in dogs with progressive retinal atrophy (PRA)"@en . . "4" . "The retinal fascin 2 gene (FSCN2) underwent a molecular analysis, a search for polymorphisms and an evaluation as a candidate gene for retinopathies in dogs. Specific fragments of the gene encompassing partial exon 1 and intron 1, and exons 2-5 with respective introns were sequenced and these data were deposited in the GenBank database. Three distinct polymorphic sites detectable with PCR-RFLP were found - AM050719: g.237G > A, AM050719: g.525A > G, and AM050720: g.1071A > G. No positive associations between these polymorphisms and the PRA-clinical status were observed in the investigated population consisting of Poodles, American Cocker Spaniels, and English Cocker Spaniels. In spite of that, the FSCN2 gene remains an excellent candidate gene for retinopathies in dogs and the results can contribute to further research in this field." . "RIV/67985904:_____/06:00045049" . "2"^^ . "3"^^ . . "Hor\u00E1k, Pavel" . . "1234-1983" . . "The retinal fascin 2 gene (FSCN2) underwent a molecular analysis, a search for polymorphisms and an evaluation as a candidate gene for retinopathies in dogs. Specific fragments of the gene encompassing partial exon 1 and intron 1, and exons 2-5 with respective introns were sequenced and these data were deposited in the GenBank database. Three distinct polymorphic sites detectable with PCR-RFLP were found - AM050719: g.237G > A, AM050719: g.525A > G, and AM050720: g.1071A > G. No positive associations between these polymorphisms and the PRA-clinical status were observed in the investigated population consisting of Poodles, American Cocker Spaniels, and English Cocker Spaniels. In spite of that, the FSCN2 gene remains an excellent candidate gene for retinopathies in dogs and the results can contribute to further research in this field."@en . . "497456" . "CZ - \u010Cesk\u00E1 republika" . "The retinal fascin gene 2 (FSCN2) - partial structural analysis and polymorphisms detection in dogs with progressive retinal atrophy (PRA)" . "The retinal fascin gene 2 (FSCN2) - partial structural analysis and polymorphisms detection in dogs with progressive retinal atrophy (PRA)" . "Gen retin\u00E1ln\u00EDho fascinu 2 (FSCN2) byl podroben molekul\u00E1rn\u00ED anal\u00FDze, vyhled\u00E1v\u00E1n\u00ED polymorfismu a hodnocen\u00ED jako kandid\u00E1tn\u00EDho genu pro retinopatie u ps\u016F. Oblasti genu zahrnuj\u00EDc\u00ED \u010D\u00E1ste\u010Dn\u00FD exon 1 a intron 1 a exony 2-5 s p\u0159\u00EDslu\u0161n\u00FDmi introny byly sekvenov\u00E1ny a sekvence byly ulo\u017Eeny v datab\u00E1zi GenBank. V genu byly identifikov\u00E1ny t\u0159i PCR-RFLP polymorfismy - AM050719:g.237G>A, AM050719:g.525A>G, a AM050720:g.1071A>G. A\u010Dkoli nebyly objeveny \u017E\u00E1dn\u00E9 pozitivn\u00ED asociace mezi uveden\u00FDmi polymorfismy a progresivn\u00ED retin\u00E1ln\u00ED atrofi\u00ED ve zkouman\u00E9 populaci plemen pudl, americk\u00FD kokr\u0161pan\u011Bl a anglick\u00FD kokr\u0161pan\u011Bl, z\u016Fst\u00E1v\u00E1 gen FSCN2 zaj\u00EDmav\u00FDm kandid\u00E1tn\u00EDm genem pro d\u011Bdi\u010Dn\u00E1 onemocn\u011Bn\u00ED s\u00EDtnice u ps\u016F."@cs . "361;364" . . . "4"^^ . "The retinal fascin gene 2 (FSCN2) - partial structural analysis and polymorphisms detection in dogs with progressive retinal atrophy (PRA)"@en . "47" . "Dvo\u0159\u00E1k, J." . . . . . . .