. "9"^^ . . . "Karen, Petr" . "BioMed Research International" . . . . "4"^^ . . . "RIV/67985823:_____/14:00428048!RIV15-GA0-67985823" . . "000332565500001" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . "10.1155/2014/289361" . "8820" . "I, P(GAP304/12/0259)" . "The activation of calcium-dependent chloride channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase calcium entry. Hypertension and ageing are associated with altered calcium handling including possible activation of calcium-dependent chloride channels. Our study was aimed to determine calcium -dependent chloride channels contribution to norepinephrine-induced contraction during hypertension and ageing. We have found that contribution of calcium -dependent chloride channels to norepinephrine-induced contraction diminished with age, hypertension development, and/or NO synthesis inhibition" . "Behuliak, Michal" . "[6711CB378D90]" . "Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing" . "Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing" . "2014" . "2014" . "2314-6133" . "Zicha, Josef" . "calcium-dependent chloride channels; endothelium-derived contracting factor; ageing"@en . . "Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing"@en . "L\u00ED\u0161kov\u00E1, Silvia" . . . . "Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing"@en . "RIV/67985823:_____/14:00428048" . "Petrov\u00E1, M." . . . "Behuliak, Michal" . "The activation of calcium-dependent chloride channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase calcium entry. Hypertension and ageing are associated with altered calcium handling including possible activation of calcium-dependent chloride channels. Our study was aimed to determine calcium -dependent chloride channels contribution to norepinephrine-induced contraction during hypertension and ageing. We have found that contribution of calcium -dependent chloride channels to norepinephrine-induced contraction diminished with age, hypertension development, and/or NO synthesis inhibition"@en . . . "5"^^ .