. . . . . "000328901900004" . "95088" . . . . . . . . . "Suppl.1" . . "62" . "0862-8408" . . "Oxidative stress in immature brain following experimentally-induced seizures"@en . "CZ - \u010Cesk\u00E1 republika" . "1"^^ . "RIV/67985823:_____/13:00422469" . . "Oxidative stress in immature brain following experimentally-induced seizures" . . "Status epilepticus (SE) induced in immature rats is associated with oxidative stress and mitochondrial dysfunction. Oxidative stress is apparently due to both the increased free radicals production and the limited antioxidant defense. Pronounced inhibition of mitochondrial complex I activity was demonstrated already during the acute phase of SE and it persists during long periods of survival following SE. The findings suggest that oxidative modification of the enzyme is most likely responsible for the sustained deficiency of complex I activity"@en . "Oxidative stress in immature brain following experimentally-induced seizures"@en . . "immature rats; experimentally-induced seizures; oxidative stress; mitochondrial dysfunction; antioxidant defense"@en . "1"^^ . . "RIV/67985823:_____/13:00422469!RIV14-MSM-67985823" . "Status epilepticus (SE) induced in immature rats is associated with oxidative stress and mitochondrial dysfunction. Oxidative stress is apparently due to both the increased free radicals production and the limited antioxidant defense. Pronounced inhibition of mitochondrial complex I activity was demonstrated already during the acute phase of SE and it persists during long periods of survival following SE. The findings suggest that oxidative modification of the enzyme is most likely responsible for the sustained deficiency of complex I activity" . "Physiological Research" . "[F262CD65D4AC]" . . . . . . . "I, P(GA309/05/2015), P(GA309/08/0292), P(GAP302/10/0971), P(GAP303/10/0999), P(LL1204), Z(AV0Z50110509)" . "10"^^ . "Oxidative stress in immature brain following experimentally-induced seizures" . "Folbergrov\u00E1, Jaroslava" .