"The binding of ATP to trimeric P2X receptors (P2XR) causes an enlargement of the receptor extracellular vestibule, leading to opening of the cation-selective transmembrane pore. We identified five residues in the extracellulat vestibule, V49, Y54, Q55, F324, and G325, as critical for P2X4R function"@en . "Kuzyk, Pavlo" . . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "10.1371/journal.pone.0059411" . . . . . . "90148" . . . "Tvrdo\u0148ov\u00E1, Vendula" . "V\u00E1vra, Vojt\u011Bch" . "PLoS ONE" . "8" . "RIV/67985823:_____/13:00392574!RIV14-GA0-67985823" . "[ADC4B84E4574]" . . "RIV/67985823:_____/13:00392574" . . "Zemkov\u00E1, Hana" . . "ATP; purinergic P2X receptor channels; transmembrane domain; extracellular vestibule; gating; ivermectin"@en . "Multiple Roles of the Extracellular Vestibule Amino Acid Residues in the Function of the Rat P2X4 Receptor"@en . "Rokic, Milos Boro" . "Multiple Roles of the Extracellular Vestibule Amino Acid Residues in the Function of the Rat P2X4 Receptor" . . . "11"^^ . "3" . . . "Multiple Roles of the Extracellular Vestibule Amino Acid Residues in the Function of the Rat P2X4 Receptor"@en . . . "Stojilkovic, S. S." . . . "1932-6203" . "6"^^ . . "5"^^ . . . "000316546400037" . . "I, P(GBP304/12/G069), P(IAA500110910), Z(AV0Z50110509)" . "Multiple Roles of the Extracellular Vestibule Amino Acid Residues in the Function of the Rat P2X4 Receptor" . "The binding of ATP to trimeric P2X receptors (P2XR) causes an enlargement of the receptor extracellular vestibule, leading to opening of the cation-selective transmembrane pore. We identified five residues in the extracellulat vestibule, V49, Y54, Q55, F324, and G325, as critical for P2X4R function" . "Kuzyk, Pavlo" . "Rokic, Milos Boro" . .