"aberrant sprouting; gliosis; nitric oxide; seizure; telemetry"@en . "I, P(GAP303/10/0999), Z(AV0Z50110509)" . . "Ot\u00E1hal, Jakub" . . "Using a highly selective neuronal NO synthase (nNOS) inhibitor, Nw-propyl-L-arginine (L-NPA), we investigated the effects of nNOS in the development of seizures and neurobiological changes, during status epilepticus (SE) and the early latent period, using a kainic acid (KA)-induced seizure model in C57BL/6J mice. The results suggest that nNOS plays a contributory role in seizure severity during SE and is important for neurobiological changes, associated with the development of chronic epilepsy, in the early latent period of epileptogenesis and may represent a novel target for pharmacological modulation in the treatment of epilepsy" . "10.1111/j.1460-9568.2012.08234.x" . . . . . "European Journal of Neuroscience" . "Beamer, E." . "N-w-Propyl-L-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses" . "[777E78909E4F]" . . "RIV/67985823:_____/12:00385447" . . . . . . "RIV/67985823:_____/12:00385447!RIV13-GA0-67985823" . "N-w-Propyl-L-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses"@en . . . "36" . "N-w-Propyl-L-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses"@en . "9" . . "Thippeswamy, T." . "0953-816X" . "4"^^ . . . "N-w-Propyl-L-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses" . "1"^^ . . "000310683800006" . "10"^^ . "155183" . . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "Sills, G. J." . "Using a highly selective neuronal NO synthase (nNOS) inhibitor, Nw-propyl-L-arginine (L-NPA), we investigated the effects of nNOS in the development of seizures and neurobiological changes, during status epilepticus (SE) and the early latent period, using a kainic acid (KA)-induced seizure model in C57BL/6J mice. The results suggest that nNOS plays a contributory role in seizure severity during SE and is important for neurobiological changes, associated with the development of chronic epilepsy, in the early latent period of epileptogenesis and may represent a novel target for pharmacological modulation in the treatment of epilepsy"@en . .